Rameix-Welti et al. suggest that careful monitoring of neuraminidase will reveal why some populations have developed natural resistance to oseltamivir, the antiviral drug commonly employed for influenza A and B.
Fargette et al. estimate the age of Rice yellow mottle virus using statistical analysis. Based on this knowledge, researchers may calculate the evolution timescale of other, related viruses.
Stenmark et al. provide a detailed look at how botulinum neurotoxin binds its ganglioside co-receptor on the cell surface. A better understanding of how the toxin enters the cell will aid efforts to create countermeasures to this toxin, one of the most toxic substances known.
Bär et al. show that gelsolin appears to facilitate a regulated virus egress from the nucleus to the cell periphery via (virus modified) lysosomal/late endosomal vesicles—suggesting that rodent parvoviruses can efficiently spread from cell to cell potentially in solid (tumor) tissue.
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