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Research Article

Unique Structure and Stability of HmuY, a Novel Heme-Binding Protein of Porphyromonas gingivalis

  • Halina Wójtowicz ,

    Affiliation: Laboratory of Biochemistry, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland

    These authors contributed equally to this study and share first authorship.

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  • Tibisay Guevara ,

    Affiliation: Proteolysis Lab, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona, Spain

    These authors contributed equally to this study and share first authorship.

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  • Cynthia Tallant,

    Affiliation: Proteolysis Lab, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona, Spain

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  • Mariusz Olczak,

    Affiliation: Laboratory of Biochemistry, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland

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  • Aneta Sroka,

    Affiliation: Laboratory of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland

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  • Jan Potempa,

    Affiliations: Laboratory of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland, Department of Periodontics, University of Louisville School of Dentistry, Louisville, Kentucky, United States of America

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  • Maria Solà,

    Affiliation: Structural MitoLab, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona, Spain

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  • Teresa Olczak mail,

    Teresa.Olczak@biotech.uni.wroc.pl (TO); fxgr@ibmb.csic.es (FXG-R)

    Affiliation: Laboratory of Biochemistry, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland

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  • F. Xavier Gomis-Rüth mail

    Teresa.Olczak@biotech.uni.wroc.pl (TO); fxgr@ibmb.csic.es (FXG-R)

    Affiliation: Proteolysis Lab, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona, Spain

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  • Published: May 08, 2009
  • DOI: 10.1371/journal.ppat.1000419

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Publisher's Note: Correction to Funding

Posted by PLoS_Pathogens on 11 May 2009 at 18:31 GMT

This
feature also facilitates heme transport to HmuR and into the bacterial cell. All
these data may help to develop new antibacterial agents at times in which
resistance toward antibiotics, both at intensive healthcare stations and in the
community, poses serious challenges to human health.

http://plospathogens.org/article/info:doi/10.1371/journal.ppat.1000419#article1.front1.article-meta1.abstract2.p1

There was an error in the first sentence of the Funding section. Grant BIO2009-XXXXX should read BIO200910334.

No competing interests declared.