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Research Article

Anthrax Lethal Toxin-Mediated Killing of Human and Murine Dendritic Cells Impairs the Adaptive Immune Response

  • Abdelkrim Alileche,

    Affiliation: Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

    ¤ Current address: Department of Oncology, Georgetown University Medical Center, Lombardi Cancer Center, Washington, District of Columbia, United States of America

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  • Evan R Serfass,

    Affiliation: Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Stefan M Muehlbauer,

    Affiliation: Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Steven A Porcelli,

    Affiliation: Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Jürgen Brojatsch mail

    To whom correspondence should be addressed. E-mail: brojatsc@aecom.yu.edu

    Affiliation: Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Published: October 28, 2005
  • DOI: 10.1371/journal.ppat.0010019

About the Authors

Abdelkrim Alileche, Evan R Serfass, Stefan M Muehlbauer, Steven A Porcelli, Jürgen Brojatsch
Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

Corresponding Author

Email: brojatsc@aecom.yu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

AA, SMM, and JB conceived and designed the experiments. AA, ERS, and SMM performed the experiments. AA, ERS, SMM, SAP, and JB analyzed the data. SAP contributed reagents/materials/analysis tools. JB wrote the paper. AA, ERS, SMM, and SAP edited the paper.