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Research Article

Functional and Genetic Analysis of Coronavirus Replicase-Transcriptase Proteins

  • Stanley G Sawicki,

    Affiliation: Department of Medical Microbiology and Immunology, Medical University of Ohio, Toledo, Ohio, United States of America

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  • Dorothea L Sawicki,

    Affiliation: Department of Medical Microbiology and Immunology, Medical University of Ohio, Toledo, Ohio, United States of America

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  • Diane Younker,

    Affiliation: Department of Medical Microbiology and Immunology, Medical University of Ohio, Toledo, Ohio, United States of America

    ¤a Current address: CheCS-Environmental Health Systems, Houston, Texas, United States of America

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  • Yvonne Meyer,

    Affiliation: Institute of Virology, University of Würzburg, Würzburg, Germany

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  • Volker Thiel,

    Affiliation: Institute of Virology, University of Würzburg, Würzburg, Germany

    ¤b Current address: Research Department, Cantonal Hospital, St. Gallen, Switzerland

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  • Helen Stokes,

    Affiliation: Department of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom

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  • Stuart G Siddell mail

    To whom correspondence should be addressed. E-mail: stuart.siddell@bristol.ac.uk

    Affiliation: Department of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom

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  • Published: December 09, 2005
  • DOI: 10.1371/journal.ppat.0010039

About the Authors

Stanley G Sawicki, Dorothea L Sawicki, Diane Younker
Department of Medical Microbiology and Immunology, Medical University of Ohio, Toledo, Ohio, United States of America
Yvonne Meyer, Volker Thiel
Institute of Virology, University of Würzburg, Würzburg, Germany
Helen Stokes, Stuart G Siddell
Department of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom

Corresponding Author

Email: stuart.siddell@bristol.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

S. G. Sawicki, D. L. Sawicki, and S. G. Siddell conceived and designed the experiments. S. G. Sawicki, D. L. Sawicki, D. Younker, Y. Meyer, V. Thiel, H. Stokes, and S. G. Siddell performed the experiments and analyzed the data. S. G. Sawicki, V. Thiel, and S. G. Siddell wrote the paper.