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Research Article

Cytoskeletal Components of an Invasion Machine—The Apical Complex of Toxoplasma gondii

  • Ke Hu,

    Affiliation: Department of Cell Biology, Scripps Research Institute, La Jolla, California, United States of America

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  • Jeff Johnson,

    Affiliation: Department of Cell Biology, Scripps Research Institute, La Jolla, California, United States of America

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  • Laurence Florens,

    Affiliation: The Stowers Institute for Medical Research, Kansas City, Missouri, United States of America

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  • Martin Fraunholz,

    Affiliation: Institute of Microbiology, E.-M.-Arndt University, Greifswald, Germany

    X
  • Sapna Suravajjala,

    Affiliation: Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Camille DiLullo,

    Affiliation: Department of Anatomy, Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, United States of America

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  • John Yates,

    Affiliation: Department of Cell Biology, Scripps Research Institute, La Jolla, California, United States of America

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  • David S Roos,

    Affiliation: Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • John M Murray mail

    To whom correspondence should be addressed. E-mail: murray@cellbio.med.upenn.edu

    Affiliation: Department of Cell & Developmental Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Published: February 24, 2006
  • DOI: 10.1371/journal.ppat.0020013

About the Authors

Ke Hu, Jeff Johnson, John Yates
Department of Cell Biology, Scripps Research Institute, La Jolla, California, United States of America
Laurence Florens
The Stowers Institute for Medical Research, Kansas City, Missouri, United States of America
Martin Fraunholz
Institute of Microbiology, E.-M.-Arndt University, Greifswald, Germany
Sapna Suravajjala, David S Roos
Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Camille DiLullo
Department of Anatomy, Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, United States of America
John M Murray
Department of Cell & Developmental Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Corresponding Author

Email: murray@cellbio.med.upenn.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

KH and JMM conceived and designed the experiments. KH, JJ, LF, SS, CD, and JMM performed the experiments. KH, JJ, LF, and JMM analyzed the data. KH, JY, DSR, and JMM contributed reagents/materials/analysis tools. MF and DSR suggested an important experiment. KH and JMM wrote the paper.