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Research Article

Flagellin-Deficient Legionella Mutants Evade Caspase-1- and Naip5-Mediated Macrophage Immunity

  • Tao Ren,

    Affiliation: Genetics Department, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Dario S Zamboni,

    Affiliation: Section of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, United States of America

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  • Craig R Roy,

    Affiliation: Section of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, United States of America

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  • William F Dietrich mail,

    To whom correspondence should be addressed. E-mail: dietrich@genetics.med.harvard.edu

    Affiliation: Genetics Department, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Russell E Vance

    Affiliation: Genetics Department, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Published: March 17, 2006
  • DOI: 10.1371/journal.ppat.0020018

About the Authors

Tao Ren, William F Dietrich, Russell E Vance
Genetics Department, Harvard Medical School, Boston, Massachusetts, United States of America
Dario S Zamboni, Craig R Roy
Section of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, United States of America

Corresponding Author

Email: dietrich@genetics.med.harvard.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

TR, DSZ, CRR, WFD, and REV conceived and designed the experiments. TR, DSZ, and REV performed the experiments. TR, DSZ, CRR, WFD, and REV analyzed the data. TR, DSZ, CRR, and REV contributed reagents/materials/analysis tools. TR, WFD, and REV wrote the paper.