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Research Article

Prions Adhere to Soil Minerals and Remain Infectious

  • Christopher J Johnson,

    Affiliations: Program in Cellular and Molecular Biology, University of Wisconsin Madison, Madison, Wisconsin, United States of America, Department of Animal Health and Biomedical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, Wisconsin, United States of America

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  • Kristen E Phillips,

    Affiliation: Molecular and Environmental Toxicology Center, University of Wisconsin Madison, Madison, Wisconsin, United States of America

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  • Peter T Schramm,

    Affiliation: Molecular and Environmental Toxicology Center, University of Wisconsin Madison, Madison, Wisconsin, United States of America

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  • Debbie McKenzie,

    Affiliation: Department of Animal Health and Biomedical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, Wisconsin, United States of America

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  • Judd M Aiken,

    Affiliations: Program in Cellular and Molecular Biology, University of Wisconsin Madison, Madison, Wisconsin, United States of America, Department of Animal Health and Biomedical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, Wisconsin, United States of America

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  • Joel A Pedersen mail

    To whom correspondence should be addressed. E-mail: joelpedersen@wisc.edu

    Affiliations: Molecular and Environmental Toxicology Center, University of Wisconsin Madison, Madison, Wisconsin, United States of America, Department of Soil Science, University of Wisconsin Madison, Madison, Wisconsin, United States of America

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  • Published: April 14, 2006
  • DOI: 10.1371/journal.ppat.0020032

About the Authors

Christopher J Johnson, Judd M Aiken
Program in Cellular and Molecular Biology, University of Wisconsin Madison, Madison, Wisconsin, United States of America
Christopher J Johnson, Debbie McKenzie, Judd M Aiken
Department of Animal Health and Biomedical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, Wisconsin, United States of America
Kristen E Phillips, Peter T Schramm, Joel A Pedersen
Molecular and Environmental Toxicology Center, University of Wisconsin Madison, Madison, Wisconsin, United States of America
Joel A Pedersen
Department of Soil Science, University of Wisconsin Madison, Madison, Wisconsin, United States of America

Corresponding Author

Email: joelpedersen@wisc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

CJJ, DM, JMA, and JAP conceived and designed the experiments. CJJ, KEP, and PTS performed the experiments. CJJ, KEP, PTS, DM, JMA, and JAP analyzed the data. JMA and JAP contributed reagents/materials/analysis tools. CJJ, DM, JMA, and JAP wrote the paper.