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Research Article

Foxp3 Represses Retroviral Transcription by Targeting Both NF-κB and CREB Pathways

  • Christian Grant,

    Affiliation: Viral Immunology Section, Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Unsong Oh,

    Affiliation: Viral Immunology Section, Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Kazunori Fugo,

    Affiliation: Viral Immunology Section, Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Norihiro Takenouchi,

    Affiliation: Viral Immunology Section, Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Caitlin Griffith,

    Affiliation: Viral Immunology Section, Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Karen Yao,

    Affiliation: Viral Immunology Section, Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Timothy E Newhook,

    Affiliation: Viral Immunology Section, Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Lee Ratner,

    Affiliation: Departments of Medicine, Pathology, and Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Steven Jacobson mail

    To whom correspondence should be addressed. E-mail: jacobsons@ninds.nih.gov

    Affiliation: Viral Immunology Section, Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Published: April 28, 2006
  • DOI: 10.1371/journal.ppat.0020033

About the Authors

Christian Grant, Unsong Oh, Kazunori Fugo, Norihiro Takenouchi, Caitlin Griffith, Karen Yao, Timothy E Newhook, Steven Jacobson
Viral Immunology Section, Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America
Lee Ratner
Departments of Medicine, Pathology, and Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America

Corresponding Author

Email: jacobsons@ninds.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

C. Grant, U. Oh, and S. Jacobson conceived and designed the experiments. C. Grant, U. Oh, K. Fugo, N. Takenouchi, C. Griffith, and T. E. Newhook performed the experiments. C. Grant, U. Oh, K. Fugo, N. Takenouchi, C. Griffith, K. Yao, and S. Jacobson analyzed the data. L. Ratner and S. Jacobson contributed reagents/materials/analysis tools. C. Grant and S. Jacobson wrote the paper.