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Research Article

HIV-1 Vpr-Induced Apoptosis Is Cell Cycle Dependent and Requires Bax but Not ANT

  • Joshua L Andersen,

    Affiliation: Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

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  • Jason L DeHart,

    Affiliation: Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

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  • Erik S Zimmerman,

    Affiliation: Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

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  • Orly Ardon,

    Affiliation: Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

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  • Baek Kim,

    Affiliation: Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America

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  • Guillaume Jacquot,

    Affiliation: Departement de Maladies Infectieuses, Institut Cochin, Institut National de la Santé et de la Recherche Médicale, Paris, France

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  • Serge Benichou,

    Affiliation: Departement de Maladies Infectieuses, Institut Cochin, Institut National de la Santé et de la Recherche Médicale, Paris, France

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  • Vicente Planelles mail

    To whom correspondence should be addressed. E-mail: Vicente.planelles@path.utah.edu

    Affiliation: Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

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  • Published: December 01, 2006
  • DOI: 10.1371/journal.ppat.0020127

About the Authors

Joshua L Andersen, Jason L DeHart, Erik S Zimmerman, Orly Ardon, Vicente Planelles
Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America
Baek Kim
Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America
Guillaume Jacquot, Serge Benichou
Departement de Maladies Infectieuses, Institut Cochin, Institut National de la Santé et de la Recherche Médicale, Paris, France

Corresponding Author

Email: Vicente.planelles@path.utah.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JLA, GJ, SB, and VP conceived and designed the experiments. JLA, JLD, GJ, and SB performed the experiments. JLA, JLD, GJ, SB, and VP analyzed the data. JLA, JLD, ESZ, OA, BK, and VP contributed reagents/materials/analysis tools. JLA and VP wrote the paper.