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Research Article

Effective Post-Exposure Treatment of Ebola Infection

  • Heinz Feldmann equal contributor mail,

    equal contributor Contributed equally to this work with: Heinz Feldmann, Steven M Jones

    To whom correspondence should be addressed. E-mail: Heinz_Feldmann@phac-aspc.gc.ca (HF); Steven_Jones@phac-aspc.gc.ca (SMJ)

    Affiliations: Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada, Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada

    X
  • Steven M Jones equal contributor mail,

    equal contributor Contributed equally to this work with: Heinz Feldmann, Steven M Jones

    To whom correspondence should be addressed. E-mail: Heinz_Feldmann@phac-aspc.gc.ca (HF); Steven_Jones@phac-aspc.gc.ca (SMJ)

    Affiliations: Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada, Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada, Department of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada

    X
  • Kathleen M Daddario-DiCaprio,

    Affiliations: Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, United States of America, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America

    X
  • Joan B Geisbert,

    Affiliation: Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, United States of America

    X
  • Ute Ströher,

    Affiliations: Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada, Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada

    X
  • Allen Grolla,

    Affiliation: Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada

    X
  • Mike Bray,

    Affiliation: Biodefense Clinical Research Branch, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Elizabeth A Fritz,

    Affiliation: Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, United States of America

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  • Lisa Fernando,

    Affiliation: Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada

    X
  • Friederike Feldmann,

    Affiliation: Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada

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  • Lisa E Hensley,

    Affiliation: Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, United States of America

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  • Thomas W Geisbert

    Affiliations: Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, United States of America, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America

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  • Published: January 19, 2007
  • DOI: 10.1371/journal.ppat.0030002

About the Authors

Heinz Feldmann, Steven M Jones, Ute Ströher, Allen Grolla, Lisa Fernando, Friederike Feldmann
Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
Heinz Feldmann, Steven M Jones, Ute Ströher
Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
Steven M Jones
Department of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada
Kathleen M Daddario-DiCaprio, Joan B Geisbert, Elizabeth A Fritz, Lisa E Hensley, Thomas W Geisbert
Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, United States of America
Kathleen M Daddario-DiCaprio, Thomas W Geisbert
Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America
Mike Bray
Biodefense Clinical Research Branch, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

HF, SMJ, US, MB, LEH, and TWG conceived and designed the experiments. HF, SMJ, KMDD, JBG, AG, EAF, LF, FF, LEH, and TWG performed the experiments. HF, SMJ, KMDD, JBG, US, AG, MB, EAF, LF, FF, LEH, and TWG analyzed the data. HF, SMJ, KMDD, JBG, US, AG, MB, EAF, LF, FF, LEH, and TWG contributed reagents/materials/analysis tools. HF, SMJ, and TWG wrote the paper.