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Research Article

HIV-1 Buds Predominantly at the Plasma Membrane of Primary Human Macrophages

  • Sonja Welsch,

    Affiliation: Department of Virology, University of Heidelberg, Heidelberg, Germany

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  • Oliver T Keppler,

    Affiliation: Department of Virology, University of Heidelberg, Heidelberg, Germany

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  • Anja Habermann,

    Affiliation: Department of Virology, University of Heidelberg, Heidelberg, Germany

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  • Ina Allespach,

    Affiliation: Department of Virology, University of Heidelberg, Heidelberg, Germany

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  • Jacomine Krijnse-Locker,

    Affiliation: European Molecular Biology Laboratory, Cell Biology and Biophysics Program, Heidelberg, Germany

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  • Hans-Georg Kräusslich mail

    To whom correspondence should be addressed. E-mail: hans-georg.kraeusslich@med.uni-heidelberg.de

    Affiliation: Department of Virology, University of Heidelberg, Heidelberg, Germany

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  • Published: March 23, 2007
  • DOI: 10.1371/journal.ppat.0030036

About the Authors

Sonja Welsch, Oliver T Keppler, Anja Habermann, Ina Allespach, Hans-Georg Kräusslich
Department of Virology, University of Heidelberg, Heidelberg, Germany
Jacomine Krijnse-Locker
European Molecular Biology Laboratory, Cell Biology and Biophysics Program, Heidelberg, Germany

Corresponding Author

Email: hans-georg.kraeusslich@med.uni-heidelberg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SW, OTK, JKL, and HGK conceived and designed the experiments. SW, AH, and IA performed the experiments. SW, OTK, AH, IA, and JKL analyzed the data. JKL and HGK contributed reagents/materials/analysis tools. SW, OTK, JKL, and HGK wrote the paper.