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Research Article

Type III Effector Activation via Nucleotide Binding, Phosphorylation, and Host Target Interaction

  • Darrell Desveaux equal contributor,

    equal contributor Contributed equally to this work with: Darrell Desveaux, Alex U Singer, Ai-Jiuan Wu, Brian C McNulty

    Affiliation: Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

    ¤a Current address: Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada

    X
  • Alex U Singer equal contributor,

    equal contributor Contributed equally to this work with: Darrell Desveaux, Alex U Singer, Ai-Jiuan Wu, Brian C McNulty

    Affiliation: Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

    ¤b Current address: CH Best Institute, University of Toronto, Toronto, Ontario, Canada

    X
  • Ai-Jiuan Wu equal contributor,

    equal contributor Contributed equally to this work with: Darrell Desveaux, Alex U Singer, Ai-Jiuan Wu, Brian C McNulty

    Affiliation: Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

    X
  • Brian C McNulty equal contributor,

    equal contributor Contributed equally to this work with: Darrell Desveaux, Alex U Singer, Ai-Jiuan Wu, Brian C McNulty

    Affiliation: Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

    X
  • Laura Musselwhite,

    Affiliation: Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

    X
  • Zachary Nimchuk,

    Affiliation: Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

    X
  • John Sondek,

    Affiliations: Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

    X
  • Jeffery L Dangl mail

    To whom correspondence should be addressed. E-mail: dangl@email.unc.edu

    Affiliations: Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Curriculum in Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

    X
  • Published: March 30, 2007
  • DOI: 10.1371/journal.ppat.0030048

About the Authors

Darrell Desveaux, Ai-Jiuan Wu, Brian C McNulty, Laura Musselwhite, Zachary Nimchuk, Jeffery L Dangl
Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
Alex U Singer, John Sondek
Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
John Sondek
Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
John Sondek
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
Jeffery L Dangl
Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
Jeffery L Dangl
Curriculum in Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
Jeffery L Dangl
Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Corresponding Author

Email: dangl@email.unc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

DD, AUS, AJW, BCM, ZN, JS, and JLD conceived and designed the experiments. DD, AUS, AJW, BCM, and LM performed the experiments. DD, AUS, AJW, BCM, LM, JS, and JLD analyzed the data. ZN contributed reagents/materials/analysis tools. DD, AUS, AJW, BCM, JS, and JLD wrote the paper.