# wombat urls ß PLOS Pathogens: Transcriptional Regulation of Multi-Drug Tolerance and Antibiotic-Induced Responses by the Histone-Like Protein Lsr2 in M. tuberculosis
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Research Article

Transcriptional Regulation of Multi-Drug Tolerance and Antibiotic-Induced Responses by the Histone-Like Protein Lsr2 in M. tuberculosis

  • Roberto Colangeli mail,

    To whom correspondence should be addressed. E-mail: rcolan1965@aol.com

    Affiliation: Division of Infectious Disease and the Center for Emerging Pathogens, Department of Medicine, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America

    X
  • Danica Helb,

    Affiliation: Division of Infectious Disease and the Center for Emerging Pathogens, Department of Medicine, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America

    X
  • Catherine Vilchèze,

    Affiliation: Howard Hughes Medical Institute, Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

    X
  • Manzour Hernando Hazbón,

    Affiliation: Division of Infectious Disease and the Center for Emerging Pathogens, Department of Medicine, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America

    X
  • Chee-Gun Lee,

    Affiliation: Department of Biochemistry and Molecular Biology, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America

    X
  • Hassan Safi,

    Affiliation: Division of Infectious Disease and the Center for Emerging Pathogens, Department of Medicine, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America

    X
  • Brendan Sayers,

    Affiliation: Division of Infectious Disease and the Center for Emerging Pathogens, Department of Medicine, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America

    X
  • Irene Sardone,

    Affiliation: Division of Infectious Disease and the Center for Emerging Pathogens, Department of Medicine, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America

    X
  • Marcus B Jones,

    Affiliation: Pathogen Functional Genomics Resource Center, The Institute for Genomic Research, J. Craig Venter Institute, Rockville, Maryland, United States of America

    X
  • Robert D Fleischmann,

    Affiliation: Pathogen Functional Genomics Resource Center, The Institute for Genomic Research, J. Craig Venter Institute, Rockville, Maryland, United States of America

    X
  • Scott N Peterson,

    Affiliation: Pathogen Functional Genomics Resource Center, The Institute for Genomic Research, J. Craig Venter Institute, Rockville, Maryland, United States of America

    X
  • William R Jacobs Jr.,

    Affiliation: Howard Hughes Medical Institute, Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

    X
  • David Alland

    Affiliation: Division of Infectious Disease and the Center for Emerging Pathogens, Department of Medicine, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America

    X
  • Published: June 22, 2007
  • DOI: 10.1371/journal.ppat.0030087

About the Authors

Roberto Colangeli, Danica Helb, Manzour Hernando Hazbón, Hassan Safi, Brendan Sayers, Irene Sardone, David Alland
Division of Infectious Disease and the Center for Emerging Pathogens, Department of Medicine, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
Catherine Vilchèze, William R Jacobs Jr.
Howard Hughes Medical Institute, Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America
Chee-Gun Lee
Department of Biochemistry and Molecular Biology, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
Marcus B Jones, Robert D Fleischmann, Scott N Peterson
Pathogen Functional Genomics Resource Center, The Institute for Genomic Research, J. Craig Venter Institute, Rockville, Maryland, United States of America

Corresponding Author

Email: rcolan1965@aol.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

RC, CGL, MBJ, RDF, WRJ, and DA conceived and designed the experiments. RC, DH, CV, MHH, CGL, HS, BS, IS, and MBJ performed the experiments. RC, DH, CV, MHH, CGL, HS, IS, MBJ, RDF, SNP, and DA analyzed the data. RC, DH, MBJ, RDF, SNP, and WRJ contributed reagents/materials/analysis tools. RC, DH, WRJ, and DA wrote the paper.