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Research Article

Plasmodium Strain Determines Dendritic Cell Function Essential for Survival from Malaria

  • Michelle N Wykes,

    Affiliation: The Queensland Institute of Medical Research, Brisbane, Queensland, Australia

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  • Xue Q Liu,

    Affiliation: The Queensland Institute of Medical Research, Brisbane, Queensland, Australia

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  • Lynette Beattie,

    Affiliations: The Queensland Institute of Medical Research, Brisbane, Queensland, Australia, Immunology and Infection Unit, University of York, York, United Kingdom

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  • Danielle I Stanisic,

    Affiliations: The Queensland Institute of Medical Research, Brisbane, Queensland, Australia, Infection and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia

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  • Katryn J Stacey,

    Affiliation: Institute for Molecular Bioscience, CRC for Chronic Inflammatory Diseases, University of Queensland, Brisbane, Queensland, Australia

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  • Mark J Smyth,

    Affiliation: Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia

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  • Ranjeny Thomas,

    Affiliation: Centre for Immunology and Cancer Research, University of Queensland, Woolloongabba, Queensland, Australia

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  • Michael F Good mail

    To whom correspondence should be addressed. E-mail: Michael.Good@qimr.edu.au

    Affiliation: The Queensland Institute of Medical Research, Brisbane, Queensland, Australia

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  • Published: July 06, 2007
  • DOI: 10.1371/journal.ppat.0030096

About the Authors

Michelle N Wykes, Xue Q Liu, Lynette Beattie, Danielle I Stanisic, Michael F Good
The Queensland Institute of Medical Research, Brisbane, Queensland, Australia
Lynette Beattie
Immunology and Infection Unit, University of York, York, United Kingdom
Danielle I Stanisic
Infection and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
Katryn J Stacey
Institute for Molecular Bioscience, CRC for Chronic Inflammatory Diseases, University of Queensland, Brisbane, Queensland, Australia
Mark J Smyth
Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
Ranjeny Thomas
Centre for Immunology and Cancer Research, University of Queensland, Woolloongabba, Queensland, Australia

Corresponding Author

Email: Michael.Good@qimr.edu.au

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

MNW, RT, and MFG conceived and designed the experiments. MNW, XQL, LB, and DIS performed the experiments. MNW analysed the data. MNW, KJS, and MJS contributed reagents/materials/analysis tools. MNW and MFG wrote the paper.