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Research Article

Dual Targeting of Antioxidant and Metabolic Enzymes to the Mitochondrion and the Apicoplast of Toxoplasma gondii

  • Paco Pino equal contributor,

    equal contributor Contributed equally to this work with: Paco Pino, Bernardo Javier Foth

    Affiliation: Department of Microbiology and Molecular Medicine, Centre Medical Universitaire, University of Geneva, Geneva, Switzerland

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  • Bernardo Javier Foth equal contributor,

    equal contributor Contributed equally to this work with: Paco Pino, Bernardo Javier Foth

    Affiliation: Department of Microbiology and Molecular Medicine, Centre Medical Universitaire, University of Geneva, Geneva, Switzerland

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  • Lai-Yu Kwok,

    Affiliation: Department of Microbiology and Molecular Medicine, Centre Medical Universitaire, University of Geneva, Geneva, Switzerland

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  • Lilach Sheiner,

    Affiliation: Department of Microbiology and Molecular Medicine, Centre Medical Universitaire, University of Geneva, Geneva, Switzerland

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  • Rebecca Schepers,

    Affiliation: Department of Biological Sciences, Imperial College London, London, United Kingdom

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  • Thierry Soldati,

    Affiliation: Department of Biochemistry, Sciences II, University of Geneva, Geneva, Switzerland

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  • Dominique Soldati-Favre mail

    To whom correspondence should be addressed. E-mail: dominique.soldati-favre@medecine.unige.ch

    Affiliation: Department of Microbiology and Molecular Medicine, Centre Medical Universitaire, University of Geneva, Geneva, Switzerland

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  • Published: August 31, 2007
  • DOI: 10.1371/journal.ppat.0030115

About the Authors

Paco Pino, Bernardo Javier Foth, Lai-Yu Kwok, Lilach Sheiner, Dominique Soldati-Favre
Department of Microbiology and Molecular Medicine, Centre Medical Universitaire, University of Geneva, Geneva, Switzerland
Rebecca Schepers
Department of Biological Sciences, Imperial College London, London, United Kingdom
Thierry Soldati
Department of Biochemistry, Sciences II, University of Geneva, Geneva, Switzerland

Corresponding Author

Email: dominique.soldati-favre@medecine.unige.ch

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

PP, BJF, LYK, LS, TS, and DSF conceived and designed the experiments and analyzed the data. PP, BJF, LYK, and LS performed the experiments. RS contributed reagents/materials/analysis tools. BJF and DSF wrote the paper.