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Research Article

Chronic HIV-1 Infection Frequently Fails to Protect against Superinfection

  • Anne Piantadosi equal contributor,

    equal contributor Contributed equally to this work with: Anne Piantadosi, Bhavna Chohan

    Affiliations: Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Pathobiology, University of Washington, Seattle, Washington, United States of America

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  • Bhavna Chohan equal contributor,

    equal contributor Contributed equally to this work with: Anne Piantadosi, Bhavna Chohan

    Affiliations: Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Pathobiology, University of Washington, Seattle, Washington, United States of America

    X
  • Vrasha Chohan,

    Affiliation: Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya

    X
  • R. Scott McClelland,

    Affiliations: Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya, Department of Medicine, University of Washington, Seattle, Washington, United States of America, Department of Epidemiology, University of Washington, Seattle, Washington, United States of America

    X
  • Julie Overbaugh mail

    To whom correspondence should be addressed. E-mail: joverbau@fhcrc.org

    Affiliations: Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Pathobiology, University of Washington, Seattle, Washington, United States of America

    X
  • Published: November 16, 2007
  • DOI: 10.1371/journal.ppat.0030177

About the Authors

Anne Piantadosi, Bhavna Chohan, Julie Overbaugh
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
Anne Piantadosi, Bhavna Chohan, Julie Overbaugh
Department of Pathobiology, University of Washington, Seattle, Washington, United States of America
Vrasha Chohan, R. Scott McClelland
Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya
R. Scott McClelland
Department of Medicine, University of Washington, Seattle, Washington, United States of America
R. Scott McClelland
Department of Epidemiology, University of Washington, Seattle, Washington, United States of America

Corresponding Author

Email: joverbau@fhcrc.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JO conceived and designed the experiments. AP and BC performed the experiments and analyzed the data. AP, BC, and JO wrote the paper. BC and VC oversaw the laboratory aspects of this study related to the cohort, including serving as liaison between clinical and laboratory staff. RSM oversaw clinical aspects of the cohort, including directing clinical monitoring and follow-up. JO oversaw all aspects of this research project.