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Research Article

Apicoplast Lipoic Acid Protein Ligase B Is Not Essential for Plasmodium falciparum

  • Svenja Günther,

    Affiliations: Division of Infection and Immunity, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow, United Kingdom, Wellcome Centre for Parasitology, Glasgow, United Kingdom

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  • Lynsey Wallace,

    Affiliations: Division of Infection and Immunity, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow, United Kingdom, Wellcome Centre for Parasitology, Glasgow, United Kingdom

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  • Eva-Maria Patzewitz,

    Affiliations: Division of Infection and Immunity, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow, United Kingdom, Wellcome Centre for Parasitology, Glasgow, United Kingdom

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  • Paul J McMillan,

    Affiliations: Division of Infection and Immunity, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow, United Kingdom, Wellcome Centre for Parasitology, Glasgow, United Kingdom

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  • Janet Storm,

    Affiliations: Division of Infection and Immunity, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow, United Kingdom, Wellcome Centre for Parasitology, Glasgow, United Kingdom

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  • Carsten Wrenger,

    Affiliation: Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany

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  • Ryan Bissett,

    Affiliations: Division of Infection and Immunity, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow, United Kingdom, Wellcome Centre for Parasitology, Glasgow, United Kingdom

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  • Terry K Smith,

    Affiliation: Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, United Kingdom

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  • Sylke Müller mail

    To whom correspondence should be addressed. E-mail: s.muller@bio.gla.ac.uk

    Affiliations: Division of Infection and Immunity, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow, United Kingdom, Wellcome Centre for Parasitology, Glasgow, United Kingdom

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  • Published: December 07, 2007
  • DOI: 10.1371/journal.ppat.0030189

About the Authors

Svenja Günther, Lynsey Wallace, Eva-Maria Patzewitz, Paul J McMillan, Janet Storm, Ryan Bissett, Sylke Müller
Division of Infection and Immunity, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow, United Kingdom
Svenja Günther, Lynsey Wallace, Eva-Maria Patzewitz, Paul J McMillan, Janet Storm, Ryan Bissett, Sylke Müller
Wellcome Centre for Parasitology, Glasgow, United Kingdom
Carsten Wrenger
Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
Terry K Smith
Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, United Kingdom

Corresponding Author

Email: s.muller@bio.gla.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SM conceived and designed the experiments. SG, LW, EMP, PJM, JS, CW, RB, TKS, and SM performed the experiments. SG, TKS, and SM analyzed the data. TKS contributed reagents/materials/analysis tools. SM wrote the paper.