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Research Article

The Effect of Trim5 Polymorphisms on the Clinical Course of HIV-1 Infection

  • Daniëlle van Manen,

    Affiliations: Department of Clinical Viro Immunology, Sanquin Research, Landsteiner Laboratory, University of Amsterdam, Amsterdam, The Netherlands, Center of Infection and Immunity Amsterdam (CINIMA), University of Amsterdam, Amsterdam, The Netherlands

    ¤ Current address: Department of Experimental Immunology, Amsterdam Medical Center, Amsterdam, The Netherlands

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  • Maarten A. N Rits,

    Affiliations: Department of Clinical Viro Immunology, Sanquin Research, Landsteiner Laboratory, University of Amsterdam, Amsterdam, The Netherlands, Center of Infection and Immunity Amsterdam (CINIMA), University of Amsterdam, Amsterdam, The Netherlands

    ¤ Current address: Department of Experimental Immunology, Amsterdam Medical Center, Amsterdam, The Netherlands

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  • Corrine Beugeling,

    Affiliations: Department of Clinical Viro Immunology, Sanquin Research, Landsteiner Laboratory, University of Amsterdam, Amsterdam, The Netherlands, Center of Infection and Immunity Amsterdam (CINIMA), University of Amsterdam, Amsterdam, The Netherlands

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  • Karel van Dort,

    Affiliations: Department of Clinical Viro Immunology, Sanquin Research, Landsteiner Laboratory, University of Amsterdam, Amsterdam, The Netherlands, Center of Infection and Immunity Amsterdam (CINIMA), University of Amsterdam, Amsterdam, The Netherlands

    ¤ Current address: Department of Experimental Immunology, Amsterdam Medical Center, Amsterdam, The Netherlands

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  • Hanneke Schuitemaker,

    Affiliations: Department of Clinical Viro Immunology, Sanquin Research, Landsteiner Laboratory, University of Amsterdam, Amsterdam, The Netherlands, Center of Infection and Immunity Amsterdam (CINIMA), University of Amsterdam, Amsterdam, The Netherlands, Department of Experimental Immunology, Amsterdam Medical Center, Amsterdam, The Netherlands

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  • Neeltje A Kootstra mail

    To whom correspondence should be addressed. E-mail: N.A.Kootstra@amc.uva.nl

    Affiliations: Department of Clinical Viro Immunology, Sanquin Research, Landsteiner Laboratory, University of Amsterdam, Amsterdam, The Netherlands, Center of Infection and Immunity Amsterdam (CINIMA), University of Amsterdam, Amsterdam, The Netherlands

    ¤ Current address: Department of Experimental Immunology, Amsterdam Medical Center, Amsterdam, The Netherlands

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  • Published: February 01, 2008
  • DOI: 10.1371/journal.ppat.0040018

About the Authors

Daniëlle van Manen, Maarten A. N Rits, Corrine Beugeling, Karel van Dort, Hanneke Schuitemaker, Neeltje A Kootstra
Department of Clinical Viro Immunology, Sanquin Research, Landsteiner Laboratory, University of Amsterdam, Amsterdam, The Netherlands
Daniëlle van Manen, Maarten A. N Rits, Corrine Beugeling, Karel van Dort, Hanneke Schuitemaker, Neeltje A Kootstra
Center of Infection and Immunity Amsterdam (CINIMA), University of Amsterdam, Amsterdam, The Netherlands
Hanneke Schuitemaker
Department of Experimental Immunology, Amsterdam Medical Center, Amsterdam, The Netherlands

Corresponding Author

Email: N.A.Kootstra@amc.uva.nl

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

HS and NAK conceived and designed the experiments and wrote the paper. DvM, MANR, CB, and KvD performed the experiments. DvM and NAK analyzed the data.