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Research Article

A Role for NKG2D in NK Cell–Mediated Resistance to Poxvirus Disease

  • Min Fang,

    Affiliation: Program of Viral Pathogenesis, Division of Basic Sciences, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America

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  • Lewis L Lanier,

    Affiliations: Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California, United States of America, Cancer Research Institute, University of California San Francisco, San Francisco, California, United States of America

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  • Luis J Sigal mail

    To whom correspondence should be addressed. E-mail: Luis.Sigal@FCCC.edu

    Affiliation: Program of Viral Pathogenesis, Division of Basic Sciences, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America

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  • Published: February 08, 2008
  • DOI: 10.1371/journal.ppat.0040030

About the Authors

Min Fang, Luis J Sigal
Program of Viral Pathogenesis, Division of Basic Sciences, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America
Lewis L Lanier
Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California, United States of America
Lewis L Lanier
Cancer Research Institute, University of California San Francisco, San Francisco, California, United States of America

Corresponding Author

Email: Luis.Sigal@FCCC.edu

Competing Interests

LLL and the University of California (San Francisco, CA) have licensed intellectual property rights relating to NKG2D for commercial applications. The authors declare that no other competing interests exist.

Author Contributions

MF, LLL, and LJS designed research. MF performed research. LLL and LJS contributed reagents and analytic tools. MF, LLL, and LJS analyzed data. MF and LJS wrote the paper. MF, LLL, and LJS approved the final manuscript.