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Research Article

The Malaria Secretome: From Algorithms to Essential Function in Blood Stage Infection

  • Christiaan van Ooij,

    Affiliation: Department of Pathology, Northwestern University, Chicago, Illinois, United States of America

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  • Pamela Tamez,

    Affiliation: Department of Pathology, Northwestern University, Chicago, Illinois, United States of America

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  • Souvik Bhattacharjee,

    Affiliation: Department of Pathology, Northwestern University, Chicago, Illinois, United States of America

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  • N. Luisa Hiller,

    Affiliation: Department of Pathology, Northwestern University, Chicago, Illinois, United States of America

    Current address: Allegheny General Hospital, Allegheny-Singer Research Institute, Center for Genomic Sciences, Pittsburgh, Pennsylvania, United States of America

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  • Travis Harrison,

    Affiliation: Department of Pathology, Northwestern University, Chicago, Illinois, United States of America

    Current address: Integrated Genomics, Chicago, Illinois, United States of America

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  • Konstantinos Liolios,

    Affiliation: Department of Pathology, Northwestern University, Chicago, Illinois, United States of America

    Current address: Department of Medicine, University of Chicago, Chicago, Illinois, United States of America

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  • Taco Kooij,

    Affiliation: Department of Parasitology, Malaria Group, Leiden University Medical Center, Leiden, The Netherlands

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  • Jai Ramesar,

    Affiliation: Department of Parasitology, Malaria Group, Leiden University Medical Center, Leiden, The Netherlands

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  • Bharath Balu,

    Affiliation: Center for Global Health and Infectious Diseases, Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, United States of America

    Current address: Global Health Infectious Disease Research (GHIDR) Program, Department of Global Health, College of Public Health, University of South Florida, Tampa, Florida, United States of America

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  • John Adams,

    Affiliation: Center for Global Health and Infectious Diseases, Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, United States of America

    Current address: Global Health Infectious Disease Research (GHIDR) Program, Department of Global Health, College of Public Health, University of South Florida, Tampa, Florida, United States of America

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  • Andy Waters,

    Affiliation: Department of Parasitology, Malaria Group, Leiden University Medical Center, Leiden, The Netherlands

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  • Chris Janse,

    Affiliation: Department of Parasitology, Malaria Group, Leiden University Medical Center, Leiden, The Netherlands

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  • Kasturi Haldar mail

    k-haldar@northwestern.edu

    Affiliations: Department of Pathology, Northwestern University, Chicago, Illinois, United States of America, Department of Microbiology and Immunology, Northwestern University, Chicago, Illinois, United States of America

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  • Published: June 13, 2008
  • DOI: 10.1371/journal.ppat.1000084

About the Authors

Christiaan van Ooij, Pamela Tamez, Souvik Bhattacharjee, N. Luisa Hiller, Travis Harrison, Konstantinos Liolios, Kasturi Haldar
Department of Pathology, Northwestern University, Chicago, Illinois, United States of America
Taco Kooij, Jai Ramesar, Andy Waters, Chris Janse
Department of Parasitology, Malaria Group, Leiden University Medical Center, Leiden, The Netherlands
Bharath Balu, John Adams
Center for Global Health and Infectious Diseases, Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, United States of America
Kasturi Haldar
Department of Microbiology and Immunology, Northwestern University, Chicago, Illinois, United States of America

Corresponding Author

Email: k-haldar@northwestern.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CV KH. Performed the experiments: CV PT JR CJ KH. Analyzed the data: CV PT NH TH CJ KH. Contributed reagents/materials/analysis tools: CV PT SB NH TH KL TK BB JA AW. Wrote the paper: CV KH.