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Research Article

Transmission of Vibrio cholerae Is Antagonized by Lytic Phage and Entry into the Aquatic Environment

  • Eric J. Nelson,

    Affiliation: Howard Hughes Medical Institute and the Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

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  • Ashrafuzzaman Chowdhury,

    Affiliation: Microbiology Department, Jahangirnagar University, Savar, Dhaka, Bangladesh

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  • James Flynn,

    Affiliation: Tufts Expression Array Core (TEAC) Facility, Tufts University School of Medicine, Boston, Massachusetts, United States of America

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  • Stefan Schild,

    Affiliation: Institut fuer Molekulare Biowissenschaften, Karl-Franzens-Universitaet Graz, Graz, Austria

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  • Lori Bourassa,

    Affiliation: Howard Hughes Medical Institute and the Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

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  • Yue Shao,

    Affiliation: Tufts Expression Array Core (TEAC) Facility, Tufts University School of Medicine, Boston, Massachusetts, United States of America

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  • Regina C. LaRocque,

    Affiliation: Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, United States of America, and Harvard Medical School, Boston, Massachusetts, United States of America

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  • Stephen B. Calderwood,

    Affiliation: Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, United States of America, and Harvard Medical School, Boston, Massachusetts, United States of America

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  • Firdausi Qadri,

    Affiliation: International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh

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  • Andrew Camilli mail

    andrew.camilli@tufts.edu

    Affiliation: Howard Hughes Medical Institute and the Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

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  • Published: October 24, 2008
  • DOI: 10.1371/journal.ppat.1000187

About the Authors

Eric J. Nelson, Lori Bourassa, Andrew Camilli
Howard Hughes Medical Institute and the Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America
Ashrafuzzaman Chowdhury
Microbiology Department, Jahangirnagar University, Savar, Dhaka, Bangladesh
James Flynn, Yue Shao
Tufts Expression Array Core (TEAC) Facility, Tufts University School of Medicine, Boston, Massachusetts, United States of America
Stefan Schild
Institut fuer Molekulare Biowissenschaften, Karl-Franzens-Universitaet Graz, Graz, Austria
Regina C. LaRocque, Stephen B. Calderwood
Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, United States of America, and Harvard Medical School, Boston, Massachusetts, United States of America
Firdausi Qadri
International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh

Corresponding Author

Email: andrew.camilli@tufts.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: E. Nelson, J. Flynn, S. Schild, L. Bourassa, R. LaRocque, S. Calderwood, F. Qadri, A. Camilli. Performed the experiments: E. Nelson, A. Chowdhury, S. Schild, L. Bourassa, Y. Shao. Analyzed the data: E. Nelson, J. Flynn, A. Camilli. Contributed reagents/materials/analysis tools: E. Nelson, J. Flynn, R. LaRocque, S. Calderwood, F. Qadri, A. Camilli. Wrote the paper: E. Nelson, A. Camilli.