Advertisement
Research Article

Repetitive N-WASP–Binding Elements of the Enterohemorrhagic Escherichia coli Effector EspFU Synergistically Activate Actin Assembly

  • Kenneth G. Campellone,

    Affiliation: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California United States of America

    X
  • Hui-Chun Cheng,

    Affiliation: Department of Biochemistry and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

    X
  • Douglas Robbins,

    Affiliation: Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

    X
  • Anosha D. Siripala,

    Affiliation: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California United States of America

    X
  • Emma J. McGhie,

    Affiliation: Department of Pathology, University of Cambridge, Cambridge, United Kingdom

    X
  • Richard D. Hayward,

    Affiliation: Department of Pathology, University of Cambridge, Cambridge, United Kingdom

    X
  • Matthew D. Welch,

    Affiliation: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California United States of America

    X
  • Michael K. Rosen,

    Affiliation: Department of Biochemistry and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

    X
  • Vassilis Koronakis,

    Affiliation: Department of Pathology, University of Cambridge, Cambridge, United Kingdom

    X
  • John M. Leong mail

    John.Leong@umassmed.edu

    Affiliation: Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

    X
  • Published: October 31, 2008
  • DOI: 10.1371/journal.ppat.1000191

About the Authors

Kenneth G. Campellone, Anosha D. Siripala, Matthew D. Welch
Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California United States of America
Hui-Chun Cheng, Michael K. Rosen
Department of Biochemistry and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
Douglas Robbins, John M. Leong
Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
Emma J. McGhie, Richard D. Hayward, Vassilis Koronakis
Department of Pathology, University of Cambridge, Cambridge, United Kingdom

Corresponding Author

Email: John.Leong@umassmed.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KGC HCC MKR. Performed the experiments: KGC HCC DR. Analyzed the data: KGC HCC DR EJM RDH MKR VK JML. Contributed reagents/materials/analysis tools: HCC ADS EJM RDH MW MKR VK JML. Wrote the paper: KGC JML.