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Research Article

Resistance of Bovine Spongiform Encephalopathy (BSE) Prions to Inactivation

  • Kurt Giles,

    Affiliations: Institute for Neurodegenerative Diseases, University of California San Francisco, San Francisco, California, United States of America, Department of Neurology, University of California San Francisco, San Francisco, California, United States of America

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  • David V. Glidden,

    Affiliation: Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America

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  • Robyn Beckwith,

    Affiliation: Institute for Neurodegenerative Diseases, University of California San Francisco, San Francisco, California, United States of America

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  • Rose Seoanes,

    Affiliation: Institute for Neurodegenerative Diseases, University of California San Francisco, San Francisco, California, United States of America

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  • David Peretz,

    Affiliations: Institute for Neurodegenerative Diseases, University of California San Francisco, San Francisco, California, United States of America, Department of Neurology, University of California San Francisco, San Francisco, California, United States of America

    Current address: Novartis Vaccines and Diagnostics, Emeryville, California, United States of America

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  • Stephen J. DeArmond,

    Affiliations: Institute for Neurodegenerative Diseases, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

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  • Stanley B. Prusiner mail

    stanley@ind.ucsf.edu

    Affiliations: Institute for Neurodegenerative Diseases, University of California San Francisco, San Francisco, California, United States of America, Department of Neurology, University of California San Francisco, San Francisco, California, United States of America, Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America

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  • Published: November 14, 2008
  • DOI: 10.1371/journal.ppat.1000206

About the Authors

Kurt Giles, Robyn Beckwith, Rose Seoanes, David Peretz, Stephen J. DeArmond, Stanley B. Prusiner
Institute for Neurodegenerative Diseases, University of California San Francisco, San Francisco, California, United States of America
Kurt Giles, David Peretz, Stanley B. Prusiner
Department of Neurology, University of California San Francisco, San Francisco, California, United States of America
David V. Glidden
Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America
Stephen J. DeArmond
Department of Pathology, University of California San Francisco, San Francisco, California, United States of America
Stanley B. Prusiner
Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America

Corresponding Author

Email: stanley@ind.ucsf.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KG DP SBP. Performed the experiments: KG DVG RB RS SJD. Analyzed the data: KG DVG RB RS SJD SBP. Wrote the paper: KG DVG SJD SBP.