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Research Article

A Critical Role of a Cellular Membrane Traffic Protein in Poliovirus RNA Replication

  • George A. Belov,

    Affiliation: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Qian Feng,

    Affiliation: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

    Current address: Radboud University, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands

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  • Krisztina Nikovics,

    Affiliation: Laboratoire d'Enzymologie et Biochimie Structurales, CNRS, Gif-sur-Yvette, France

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  • Catherine L. Jackson,

    Affiliation: Laboratoire d'Enzymologie et Biochimie Structurales, CNRS, Gif-sur-Yvette, France

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  • Ellie Ehrenfeld mail

    eehrenfeld@niaid.nih.gov

    Affiliation: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Published: November 21, 2008
  • DOI: 10.1371/journal.ppat.1000216

About the Authors

George A. Belov, Qian Feng, Ellie Ehrenfeld
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
Krisztina Nikovics, Catherine L. Jackson
Laboratoire d'Enzymologie et Biochimie Structurales, CNRS, Gif-sur-Yvette, France

Corresponding Author

Email: eehrenfeld@niaid.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GAB CLJ EE. Performed the experiments: GAB QF KN. Analyzed the data: QF KN CLJ EE. Wrote the paper: GAB CLJ EE.