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Research Article

Detailed Analysis of Sequence Changes Occurring during vlsE Antigenic Variation in the Mouse Model of Borrelia burgdorferi Infection

  • Loïc Coutte,

    Affiliation: Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, Houston, Texas, United States of America

    Current address: Institut de Biologie de Lille, Lille, France

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  • Douglas J. Botkin,

    Affiliations: Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, Houston, Texas, United States of America, Department of Microbiology and Molecular Genetics, University of Texas Medical School at Houston, Houston, Texas, United States of America

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  • Lihui Gao,

    Affiliation: Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, Houston, Texas, United States of America

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  • Steven J. Norris mail

    Steven.J.Norris@uth.tmc.edu

    Affiliations: Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, Houston, Texas, United States of America, Department of Microbiology and Molecular Genetics, University of Texas Medical School at Houston, Houston, Texas, United States of America

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  • Published: February 13, 2009
  • DOI: 10.1371/journal.ppat.1000293

About the Authors

Loïc Coutte, Douglas J. Botkin, Lihui Gao, Steven J. Norris
Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, Houston, Texas, United States of America
Douglas J. Botkin, Steven J. Norris
Department of Microbiology and Molecular Genetics, University of Texas Medical School at Houston, Houston, Texas, United States of America

Corresponding Author

Email: Steven.J.Norris@uth.tmc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LC LG SJN. Performed the experiments: LC LG. Analyzed the data: LC DJB LG SJN. Contributed reagents/materials/analysis tools: LC DJB. Wrote the paper: LC SJN.