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Research Article

Transcriptional Profiling in Pathogenic and Non-Pathogenic SIV Infections Reveals Significant Distinctions in Kinetics and Tissue Compartmentalization

  • Sharon Lederer equal contributor,

    equal contributor Contributed equally to this work with: Sharon Lederer, David Favre

    Affiliation: Department of Microbiology, University of Washington, Seattle, Washington, United States of America

    X
  • David Favre equal contributor,

    equal contributor Contributed equally to this work with: Sharon Lederer, David Favre

    Affiliation: Department of Medicine, Division of Experimental Medicine, University of California, San Francisco, California, United States of America

    X
  • Kathie-Anne Walters,

    Affiliation: Department of Microbiology, University of Washington, Seattle, Washington, United States of America

    X
  • Sean Proll,

    Affiliation: Department of Microbiology, University of Washington, Seattle, Washington, United States of America

    X
  • Bittoo Kanwar,

    Affiliations: Department of Medicine, Division of Experimental Medicine, University of California, San Francisco, California, United States of America, Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, University of California, San Francisco, California, United States of America

    X
  • Zeljka Kasakow,

    Affiliation: Department of Medicine, Division of Experimental Medicine, University of California, San Francisco, California, United States of America

    X
  • Carole R. Baskin,

    Affiliations: Department of Microbiology, University of Washington, Seattle, Washington, United States of America, Washington National Primate Research Center, University of Washington, Seattle, Washington, United States of America

    X
  • Robert Palermo,

    Affiliation: Department of Microbiology, University of Washington, Seattle, Washington, United States of America

    X
  • Joseph M. McCune,

    Affiliation: Department of Medicine, Division of Experimental Medicine, University of California, San Francisco, California, United States of America

    X
  • Michael G. Katze mail

    honey@u.washington.edu

    Affiliations: Department of Microbiology, University of Washington, Seattle, Washington, United States of America, Washington National Primate Research Center, University of Washington, Seattle, Washington, United States of America

    X
  • Published: February 13, 2009
  • DOI: 10.1371/journal.ppat.1000296

About the Authors

Sharon Lederer, Kathie-Anne Walters, Sean Proll, Carole R. Baskin, Robert Palermo, Michael G. Katze
Department of Microbiology, University of Washington, Seattle, Washington, United States of America
David Favre, Bittoo Kanwar, Zeljka Kasakow, Joseph M. McCune
Department of Medicine, Division of Experimental Medicine, University of California, San Francisco, California, United States of America
Bittoo Kanwar
Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, University of California, San Francisco, California, United States of America
Carole R. Baskin, Michael G. Katze
Washington National Primate Research Center, University of Washington, Seattle, Washington, United States of America

Corresponding Author

Email: honey@u.washington.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SLL DF CRB JMM MGK. Performed the experiments: SLL DF BK. Analyzed the data: SLL KAW. Contributed reagents/materials/analysis tools: SLL DF SP ZK MGK. Wrote the paper: SLL KAW MGK. Contributed scientific expertise: RP.