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Research Article

Extracellular Bacterial Pathogen Induces Host Cell Surface Reorganization to Resist Shear Stress

  • Guillain Mikaty,

    Affiliations: INSERM, U570, Paris, France, Université Paris Descartes, Faculté de Médecine Paris Descartes, UMR S570, Paris, France

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  • Magali Soyer,

    Affiliations: INSERM, U570, Paris, France, Université Paris Descartes, Faculté de Médecine Paris Descartes, UMR S570, Paris, France

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  • Emilie Mairey,

    Affiliations: INSERM, U570, Paris, France, Université Paris Descartes, Faculté de Médecine Paris Descartes, UMR S570, Paris, France

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  • Nelly Henry,

    Affiliation: CNRS, UMR 168, Paris, France

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  • Dave Dyer,

    Affiliation: University of Wisconsin-Madison, Department of Bacteriology, Madison, Wisconsin, United States of America

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  • Katrina T. Forest,

    Affiliation: University of Wisconsin-Madison, Department of Bacteriology, Madison, Wisconsin, United States of America

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  • Philippe Morand,

    Affiliations: INSERM, U570, Paris, France, Université Paris Descartes, Faculté de Médecine Paris Descartes, UMR S570, Paris, France

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  • Stéphanie Guadagnini,

    Affiliation: Plate-Forme de Microscopie Electronique, Institut Pasteur, Paris, France

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  • Marie Christine Prévost,

    Affiliation: Plate-Forme de Microscopie Electronique, Institut Pasteur, Paris, France

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  • Xavier Nassif,

    Affiliations: INSERM, U570, Paris, France, Université Paris Descartes, Faculté de Médecine Paris Descartes, UMR S570, Paris, France, AP-HP, Hôpital Necker-Enfants Malades, Paris, France

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  • Guillaume Duménil mail

    guillaume.dumenil@inserm.fr

    Affiliations: INSERM, U570, Paris, France, Université Paris Descartes, Faculté de Médecine Paris Descartes, UMR S570, Paris, France

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  • Published: February 27, 2009
  • DOI: 10.1371/journal.ppat.1000314

About the Authors

Guillain Mikaty, Magali Soyer, Emilie Mairey, Philippe Morand, Xavier Nassif, Guillaume Duménil
INSERM, U570, Paris, France
Guillain Mikaty, Magali Soyer, Emilie Mairey, Philippe Morand, Xavier Nassif, Guillaume Duménil
Université Paris Descartes, Faculté de Médecine Paris Descartes, UMR S570, Paris, France
Nelly Henry
CNRS, UMR 168, Paris, France
Dave Dyer, Katrina T. Forest
University of Wisconsin-Madison, Department of Bacteriology, Madison, Wisconsin, United States of America
Stéphanie Guadagnini, Marie Christine Prévost
Plate-Forme de Microscopie Electronique, Institut Pasteur, Paris, France
Xavier Nassif
AP-HP, Hôpital Necker-Enfants Malades, Paris, France

Corresponding Author

Email: guillaume.dumenil@inserm.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GM MS EM NH XN GD. Performed the experiments: GM MS EM NH SG GD. Analyzed the data: GM MS EM NH XN GD. Contributed reagents/materials/analysis tools: NH DD KTF PCM SG MCP GD. Wrote the paper: KTF GD.