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Research Article

Abnormal Brain Iron Homeostasis in Human and Animal Prion Disorders

  • Ajay Singh equal contributor,

    equal contributor Contributed equally to this work with: Ajay Singh, Alfred Orina Isaac, Xiu Luo

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

    X
  • Alfred Orina Isaac equal contributor,

    equal contributor Contributed equally to this work with: Ajay Singh, Alfred Orina Isaac, Xiu Luo

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

    X
  • Xiu Luo equal contributor,

    equal contributor Contributed equally to this work with: Ajay Singh, Alfred Orina Isaac, Xiu Luo

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

    X
  • Maradumane L. Mohan,

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

    X
  • Mark L. Cohen,

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

    X
  • Fusong Chen,

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

    X
  • Qingzhong Kong,

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

    X
  • Jason Bartz,

    Affiliation: Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, United States of America

    X
  • Neena Singh mail

    neena.singh@case.edu

    Affiliation: Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

    X
  • Published: March 13, 2009
  • DOI: 10.1371/journal.ppat.1000336

About the Authors

Ajay Singh, Alfred Orina Isaac, Xiu Luo, Maradumane L. Mohan, Mark L. Cohen, Fusong Chen, Qingzhong Kong, Neena Singh
Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America
Jason Bartz
Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, United States of America

Corresponding Author

Email: neena.singh@case.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NS. Performed the experiments: AS AOI XL MLM. Analyzed the data: AS AOI MLc NS. Contributed reagents/materials/analysis tools: FC QK JB. Wrote the paper: NS. Proof-read and edited the paper: AS. Wrote part of the paper: AS.