Advertisement
Research Article

The Tetraspanin Protein CD37 Regulates IgA Responses and Anti-Fungal Immunity

  • Annemiek B. van Spriel,

    Affiliation: Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, University Medical Centre, Nijmegen, The Netherlands

    X
  • Mariam Sofi,

    Affiliation: Department of Immunology, Monash University, Alfred Medical Research and Education Precinct, Melbourne, Australia

    X
  • Kate H. Gartlan,

    Affiliation: Department of Immunology, Monash University, Alfred Medical Research and Education Precinct, Melbourne, Australia

    X
  • Alie van der Schaaf,

    Affiliation: Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, University Medical Centre, Nijmegen, The Netherlands

    X
  • Ineke Verschueren,

    Affiliation: Department of Medicine and Nijmegen Institute for Infections, Inflammation and Immunity (N4i), University Medical Centre, Nijmegen, The Netherlands

    X
  • Ruurd Torensma,

    Affiliation: Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, University Medical Centre, Nijmegen, The Netherlands

    X
  • Reinier A. P. Raymakers,

    Affiliation: Department of Hematology and Central Hematology Laboratory, University Medical Centre, Nijmegen, The Netherlands

    X
  • Bruce E. Loveland,

    Affiliation: Burnet Institute (Austin Campus), Heidelberg, Australia

    X
  • Mihai G. Netea,

    Affiliation: Department of Medicine and Nijmegen Institute for Infections, Inflammation and Immunity (N4i), University Medical Centre, Nijmegen, The Netherlands

    X
  • Gosse J. Adema,

    Affiliation: Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, University Medical Centre, Nijmegen, The Netherlands

    X
  • Mark D. Wright equal contributor,

    equal contributor Contributed equally to this work with: Mark D. Wright, Carl G. Figdor

    Affiliation: Department of Immunology, Monash University, Alfred Medical Research and Education Precinct, Melbourne, Australia

    X
  • Carl G. Figdor equal contributor mail

    equal contributor Contributed equally to this work with: Mark D. Wright, Carl G. Figdor

    c.figdor@ncmls.ru.nl

    Affiliation: Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, University Medical Centre, Nijmegen, The Netherlands

    X
  • Published: March 13, 2009
  • DOI: 10.1371/journal.ppat.1000338

About the Authors

Annemiek B. van Spriel, Alie van der Schaaf, Ruurd Torensma, Gosse J. Adema, Carl G. Figdor
Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, University Medical Centre, Nijmegen, The Netherlands
Mariam Sofi, Kate H. Gartlan, Mark D. Wright
Department of Immunology, Monash University, Alfred Medical Research and Education Precinct, Melbourne, Australia
Ineke Verschueren, Mihai G. Netea
Department of Medicine and Nijmegen Institute for Infections, Inflammation and Immunity (N4i), University Medical Centre, Nijmegen, The Netherlands
Reinier A. P. Raymakers
Department of Hematology and Central Hematology Laboratory, University Medical Centre, Nijmegen, The Netherlands
Bruce E. Loveland
Burnet Institute (Austin Campus), Heidelberg, Australia

Corresponding Author

Email: c.figdor@ncmls.ru.nl

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ABvS MGN GJA MDW CGF. Performed the experiments: ABvS MS KHG AvdS IV BEL. Analyzed the data: ABvS MS KHG AvdS IV RT RAPR BEL MGN GJA MDW CGF. Contributed reagents/materials/analysis tools: ABvS RT RAPR BEL MGN MDW CGF. Wrote the paper: ABvS MDW CGF.