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Research Article

Methylation-Dependent Binding of the Epstein-Barr Virus BZLF1 Protein to Viral Promoters

  • Sarah J. Dickerson,

    Affiliation: McArdle Laboratory, Departments of Oncology and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America

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  • Yongna Xing,

    Affiliation: McArdle Laboratory, Departments of Oncology and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America

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  • Amanda R. Robinson,

    Affiliation: McArdle Laboratory, Departments of Oncology and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America

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  • William T. Seaman,

    Affiliation: Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America

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  • Henri Gruffat,

    Affiliation: Laboratoire de Virologie U758, ENS-Lyon, INSERM, Lyon, France

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  • Shannon C. Kenney mail

    skenney@oncology.wisc.edu

    Affiliation: McArdle Laboratory, Departments of Oncology and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America

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  • Published: March 27, 2009
  • DOI: 10.1371/journal.ppat.1000356

About the Authors

Sarah J. Dickerson, Yongna Xing, Amanda R. Robinson, Shannon C. Kenney
McArdle Laboratory, Departments of Oncology and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America
William T. Seaman
Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America
Henri Gruffat
Laboratoire de Virologie U758, ENS-Lyon, INSERM, Lyon, France

Corresponding Author

Email: skenney@oncology.wisc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SJD SCK. Performed the experiments: SJD YX ARR WTS. Analyzed the data: SJD YX ARR WTS SCK. Contributed reagents/materials/analysis tools: YX HG. Wrote the paper: SJD SCK.