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Research Article

Likely Role of APOBEC3G-Mediated G-to-A Mutations in HIV-1 Evolution and Drug Resistance

  • Patric Jern,

    Affiliation: Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

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  • Rebecca A. Russell,

    Affiliation: HIV Drug Resistance Program, National Cancer Institute-Frederick, Frederick, Maryland, United States of America

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  • Vinay K. Pathak,

    Affiliation: HIV Drug Resistance Program, National Cancer Institute-Frederick, Frederick, Maryland, United States of America

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  • John M. Coffin mail

    john.coffin@tufts.edu

    Affiliation: Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

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  • Published: April 03, 2009
  • DOI: 10.1371/journal.ppat.1000367

About the Authors

Patric Jern, John M. Coffin
Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America
Rebecca A. Russell, Vinay K. Pathak
HIV Drug Resistance Program, National Cancer Institute-Frederick, Frederick, Maryland, United States of America

Corresponding Author

Email: john.coffin@tufts.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PJ JMC. Performed the experiments: PJ RAR JMC. Analyzed the data: PJ JMC. Contributed reagents/materials/analysis tools: PJ RAR VP JMC. Wrote the paper: PJ RAR VP JMC.