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Research Article

Vesicular Stomatitis Virus Enters Cells through Vesicles Incompletely Coated with Clathrin That Depend upon Actin for Internalization

  • David K. Cureton,

    Affiliations: Departments of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Program in Virology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Ramiro H. Massol,

    Affiliations: Children’s Hospital, Boston, Massachusetts, United States of America, Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Immune Disease Institute, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Saveez Saffarian,

    Affiliations: Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Immune Disease Institute, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Tomas L. Kirchhausen mail,

    kirchhausen@crystal.harvard.edu (TLK); swhelan@hms.harvard.edu (SPJW)

    Affiliations: Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Immune Disease Institute, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Sean P. J. Whelan mail

    kirchhausen@crystal.harvard.edu (TLK); swhelan@hms.harvard.edu (SPJW)

    Affiliations: Departments of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Program in Virology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Published: April 24, 2009
  • DOI: 10.1371/journal.ppat.1000394

About the Authors

David K. Cureton, Sean P. J. Whelan
Departments of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
David K. Cureton, Sean P. J. Whelan
Program in Virology, Harvard Medical School, Boston, Massachusetts, United States of America
Ramiro H. Massol
Children’s Hospital, Boston, Massachusetts, United States of America
Ramiro H. Massol, Saveez Saffarian, Tomas L. Kirchhausen
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America
Ramiro H. Massol, Saveez Saffarian, Tomas L. Kirchhausen
Immune Disease Institute, Harvard Medical School, Boston, Massachusetts, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DKC RHM SS TK SPJW. Performed the experiments: DKC RHM SS TK SPJW. Analyzed the data: DKC RHM SS TK SPJW. Contributed reagents/materials/analysis tools: DKC RHM SS TK SPJW. Wrote the paper: DKC TK SPJW.