Advertisement
Research Article

Genome-Scale Multilocus Microsatellite Typing of Trypanosoma cruzi Discrete Typing Unit I Reveals Phylogeographic Structure and Specific Genotypes Linked to Human Infection

  • Martin S. Llewellyn mail,

    martin.llewellyn@lshtm.ac.uk

    Affiliation: London School of Hygiene and Tropical Medicine, London, United Kingdom

    X
  • Michael A. Miles,

    Affiliation: London School of Hygiene and Tropical Medicine, London, United Kingdom

    X
  • Hernan J. Carrasco,

    Affiliation: Instituto de Medicina Tropical, Universidad Central de Venezuela, Los Chaguaramos, Caracas, Venezuela

    X
  • Michael D. Lewis,

    Affiliation: London School of Hygiene and Tropical Medicine, London, United Kingdom

    X
  • Matthew Yeo,

    Affiliation: London School of Hygiene and Tropical Medicine, London, United Kingdom

    X
  • Jorge Vargas,

    Affiliation: Centro Nacional de Enfermedades Tropicales, Santa Cruz, Bolivia

    X
  • Faustino Torrico,

    Affiliation: Universidad Mayor de San Simon, Cochabamba, Bolivia

    X
  • Patricio Diosque,

    Affiliation: Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Patologia Experimental, Universidad Nacional de Salta, Salta, Argentina

    X
  • Vera Valente,

    Affiliation: Instituto Evandro Chagas, Rodovia, Belem, Para, Brazil

    X
  • Sebastiao A. Valente,

    Affiliation: Instituto Evandro Chagas, Rodovia, Belem, Para, Brazil

    X
  • Michael W. Gaunt

    Affiliation: London School of Hygiene and Tropical Medicine, London, United Kingdom

    X
  • Published: May 01, 2009
  • DOI: 10.1371/journal.ppat.1000410

About the Authors

Martin S. Llewellyn, Michael A. Miles, Michael D. Lewis, Matthew Yeo, Michael W. Gaunt
London School of Hygiene and Tropical Medicine, London, United Kingdom
Hernan J. Carrasco
Instituto de Medicina Tropical, Universidad Central de Venezuela, Los Chaguaramos, Caracas, Venezuela
Jorge Vargas
Centro Nacional de Enfermedades Tropicales, Santa Cruz, Bolivia
Faustino Torrico
Universidad Mayor de San Simon, Cochabamba, Bolivia
Patricio Diosque
Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Patologia Experimental, Universidad Nacional de Salta, Salta, Argentina
Vera Valente, Sebastiao A. Valente
Instituto Evandro Chagas, Rodovia, Belem, Para, Brazil

Corresponding Author

Email: martin.llewellyn@lshtm.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MSL MAM MWG. Performed the experiments: MSL HJC. Analyzed the data: MSL MDL. Contributed reagents/materials/analysis tools: HJC MDL MY JV FT PD VCV SAV. Wrote the paper: MSL MAM MDL MY.