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Research Article

Unique Structure and Stability of HmuY, a Novel Heme-Binding Protein of Porphyromonas gingivalis

  • Halina Wójtowicz ,

    Affiliation: Laboratory of Biochemistry, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland

    These authors contributed equally to this study and share first authorship.

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  • Tibisay Guevara ,

    Affiliation: Proteolysis Lab, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona, Spain

    These authors contributed equally to this study and share first authorship.

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  • Cynthia Tallant,

    Affiliation: Proteolysis Lab, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona, Spain

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  • Mariusz Olczak,

    Affiliation: Laboratory of Biochemistry, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland

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  • Aneta Sroka,

    Affiliation: Laboratory of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland

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  • Jan Potempa,

    Affiliations: Laboratory of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland, Department of Periodontics, University of Louisville School of Dentistry, Louisville, Kentucky, United States of America

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  • Maria Solà,

    Affiliation: Structural MitoLab, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona, Spain

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  • Teresa Olczak mail,

    Teresa.Olczak@biotech.uni.wroc.pl (TO); fxgr@ibmb.csic.es (FXG-R)

    Affiliation: Laboratory of Biochemistry, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland

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  • F. Xavier Gomis-Rüth mail

    Teresa.Olczak@biotech.uni.wroc.pl (TO); fxgr@ibmb.csic.es (FXG-R)

    Affiliation: Proteolysis Lab, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona, Spain

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  • Published: May 08, 2009
  • DOI: 10.1371/journal.ppat.1000419

About the Authors

Halina Wójtowicz, Mariusz Olczak, Teresa Olczak
Laboratory of Biochemistry, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland
Tibisay Guevara, Cynthia Tallant, F. Xavier Gomis-Rüth
Proteolysis Lab, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona, Spain
Aneta Sroka, Jan Potempa
Laboratory of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland
Jan Potempa
Department of Periodontics, University of Louisville School of Dentistry, Louisville, Kentucky, United States of America
Maria Solà
Structural MitoLab, Department of Structural Biology, Molecular Biology Institute of Barcelona, CSIC, Barcelona, Spain

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HW MO JP TO FXGR. Performed the experiments: HW TG CT AS MS FXGR. Analyzed the data: CT MS FXGR. Contributed reagents/materials/analysis tools: TG MO TO FXGR. Wrote the paper: JP MS FXGR.