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Research Article

Increasing Clinical Virulence in Two Decades of the Italian HIV Epidemic

  • Viktor Müller mail,

    viktor.mueller@env.ethz.ch

    Affiliation: Institute of Biology, Eötvös Loránd University, Budapest, Hungary

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  • Franco Maggiolo,

    Affiliation: Ospedali Riuniti, Bergamo, Italy

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  • Fredy Suter,

    Affiliation: Ospedali Riuniti, Bergamo, Italy

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  • Nicoletta Ladisa,

    Affiliation: Policlinico di Bari, Bari, Italy

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  • Andrea De Luca,

    Affiliation: Institute of Clinical Infectious Diseases, Catholic University, Rome, Italy

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  • Andrea Antinori,

    Affiliation: National Institute of Infectious Diseases L. Spallanzani, Rome, Italy

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  • Laura Sighinolfi,

    Affiliation: Ospedale S. Anna, Ferrara, Italy

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  • Eugenia Quiros-Roldan,

    Affiliation: Institute of Infectious and Tropical Diseases, University of Brescia, Brescia, Italy

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  • Giampiero Carosi,

    Affiliation: Institute of Infectious and Tropical Diseases, University of Brescia, Brescia, Italy

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  • Carlo Torti

    Affiliation: Institute of Infectious and Tropical Diseases, University of Brescia, Brescia, Italy

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  • Published: May 29, 2009
  • DOI: 10.1371/journal.ppat.1000454

About the Authors

Viktor Müller
Institute of Biology, Eötvös Loránd University, Budapest, Hungary
Franco Maggiolo, Fredy Suter
Ospedali Riuniti, Bergamo, Italy
Nicoletta Ladisa
Policlinico di Bari, Bari, Italy
Andrea De Luca
Institute of Clinical Infectious Diseases, Catholic University, Rome, Italy
Andrea Antinori
National Institute of Infectious Diseases L. Spallanzani, Rome, Italy
Laura Sighinolfi
Ospedale S. Anna, Ferrara, Italy
Eugenia Quiros-Roldan, Giampiero Carosi, Carlo Torti
Institute of Infectious and Tropical Diseases, University of Brescia, Brescia, Italy

Corresponding Author

Email: viktor.mueller@env.ethz.ch

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Performed the experiments: FM FS NL ADL AA LS EQR GC CT. Analyzed the data: VM. Contributed reagents/materials/analysis tools: FM FS NL ADL AA LS EQR GC CT. Wrote the paper: VM. Conceived and designed the analysis: VM CT. Designed analyses: ADL AA.