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Research Article

Genetic Detection and Characterization of Lujo Virus, a New Hemorrhagic Fever–Associated Arenavirus from Southern Africa

  • Thomas Briese equal contributor mail,

    equal contributor Contributed equally to this work with: Thomas Briese, Janusz T. Paweska

    thomas.briese@columbia.edu (TB); wil2001@columbia.edu (WIL)

    Affiliation: Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, United States of America

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  • Janusz T. Paweska equal contributor,

    equal contributor Contributed equally to this work with: Thomas Briese, Janusz T. Paweska

    Affiliation: Special Pathogens Unit, National Institute for Communicable Diseases of the National Health Laboratory Service, Sandringham, South Africa

    X
  • Laura K. McMullan,

    Affiliation: Special Pathogens Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

    X
  • Stephen K. Hutchison,

    Affiliation: 454 Life Sciences, Branford, Connecticut, United States of America

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  • Craig Street,

    Affiliation: Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, United States of America

    X
  • Gustavo Palacios,

    Affiliation: Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, United States of America

    X
  • Marina L. Khristova,

    Affiliation: Biotechnology Core Facility Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • Jacqueline Weyer,

    Affiliation: Special Pathogens Unit, National Institute for Communicable Diseases of the National Health Laboratory Service, Sandringham, South Africa

    X
  • Robert Swanepoel,

    Affiliation: Special Pathogens Unit, National Institute for Communicable Diseases of the National Health Laboratory Service, Sandringham, South Africa

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  • Michael Egholm,

    Affiliation: 454 Life Sciences, Branford, Connecticut, United States of America

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  • Stuart T. Nichol,

    Affiliation: Special Pathogens Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

    X
  • W. Ian Lipkin mail

    thomas.briese@columbia.edu (TB); wil2001@columbia.edu (WIL)

    Affiliation: Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, United States of America

    X
  • Published: May 29, 2009
  • DOI: 10.1371/journal.ppat.1000455

About the Authors

Thomas Briese, Craig Street, Gustavo Palacios, W. Ian Lipkin
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, United States of America
Janusz T. Paweska, Jacqueline Weyer, Robert Swanepoel
Special Pathogens Unit, National Institute for Communicable Diseases of the National Health Laboratory Service, Sandringham, South Africa
Laura K. McMullan, Stuart T. Nichol
Special Pathogens Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
Stephen K. Hutchison, Michael Egholm
454 Life Sciences, Branford, Connecticut, United States of America
Marina L. Khristova
Biotechnology Core Facility Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Corresponding Authors

Competing Interests

SKH and ME are employees of 454 Life Sciences, Inc., a Roche Company.

Author Contributions

Conceived and designed the experiments: TB WIL. Performed the experiments: TB JTP LKM SKH GP MLK JW. Analyzed the data: TB LKM SKH CS GP MLK ME STN WIL. Contributed reagents/materials/analysis tools: JTP CS JW BS ME. Wrote the paper: TB JTP BS STN WIL.