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Research Article

Recruitment of a SAP18-HDAC1 Complex into HIV-1 Virions and Its Requirement for Viral Replication

  • Masha Sorin equal contributor,

    equal contributor Contributed equally to this work with: Masha Sorin, Jennifer Cano

    Affiliation: Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Jennifer Cano equal contributor,

    equal contributor Contributed equally to this work with: Masha Sorin, Jennifer Cano

    Affiliation: Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Supratik Das,

    Affiliation: Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Sheeba Mathew,

    Affiliation: Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Xuhong Wu,

    Affiliation: Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Kelvin P. Davies,

    Affiliation: Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America

    Current address: Department of Urology, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Xuanling Shi,

    Affiliation: Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

    Current address: HIV Research Centre, Tsinghua University, Beijing, People's Republic of China

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  • S.-W. Grace Cheng,

    Affiliation: Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America

    Current address: Genome Sciences Centre, BC Cancer Research Centre, Vancouver, British Columbia, Canada

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  • David Ott,

    Affiliation: Basic Research Program, SAIC–Frederick Inc., National Cancer Institute–Frederick, Frederick, Maryland, United States of America

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  • Ganjam V. Kalpana mail

    kalpana@aecom.yu.edu

    Affiliations: Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America, Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Published: June 05, 2009
  • DOI: 10.1371/journal.ppat.1000463

About the Authors

Masha Sorin, Jennifer Cano, Supratik Das, Sheeba Mathew, Xuhong Wu, Kelvin P. Davies, S.-W. Grace Cheng, Ganjam V. Kalpana
Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America
Xuanling Shi, Ganjam V. Kalpana
Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America
David Ott
Basic Research Program, SAIC–Frederick Inc., National Cancer Institute–Frederick, Frederick, Maryland, United States of America

Corresponding Author

Email: kalpana@aecom.yu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MS GVK. Performed the experiments: MS JC SRD SM XW KPD XS GSWC. Analyzed the data: MS JC SM KPD GVK. Contributed reagents/materials/analysis tools: DEO GVK. Wrote the paper: MS JC GVK.