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Research Article

Genomic Diversity and Evolution of Mycobacterium ulcerans Revealed by Next-Generation Sequencing

  • Weihong Qi,

    Affiliation: Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, Basel, Switzerland

    Current address: Functional Genomics Center Zurich, UZH/ETHZ, Zurich, Switzerland

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  • Michael Käser,

    Affiliation: Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, Basel, Switzerland

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  • Katharina Röltgen,

    Affiliation: Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, Basel, Switzerland

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  • Dorothy Yeboah-Manu,

    Affiliation: Department of Bacteriology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana

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  • Gerd Pluschke mail

    Gerd.Pluschke@unibas.ch

    Affiliation: Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, Basel, Switzerland

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  • Published: September 11, 2009
  • DOI: 10.1371/journal.ppat.1000580

About the Authors

Weihong Qi, Michael Käser, Katharina Röltgen, Gerd Pluschke
Department of Medical Parasitology and Infection Biology, Swiss Tropical Institute, Basel, Switzerland
Dorothy Yeboah-Manu
Department of Bacteriology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana

Corresponding Author

Email: Gerd.Pluschke@unibas.ch

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WQ MK GP. Analyzed the data: WQ. Wrote the paper: WQ GP. Performed DNA isolation and provided DNA samples for sequencing: MK. Performed SNP confirmation and SNP assay experiments: KR. Contributed strains: DYM.