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Research Article

Getting to Grips with Strangles: An Effective Multi-Component Recombinant Vaccine for the Protection of Horses from Streptococcus equi Infection

  • Bengt Guss,

    Affiliation: Department of Microbiology, Swedish University of Agricultural Sciences, Uppsala, Sweden

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  • Margareta Flock,

    Affiliation: Department of Microbiology, Tumor and Cellbiology, Karolinska Institutet, Stockholm, Sweden

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  • Lars Frykberg,

    Affiliation: Department of Microbiology, Swedish University of Agricultural Sciences, Uppsala, Sweden

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  • Andrew S. Waller,

    Affiliation: Department of Bacteriology, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom

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  • Carl Robinson,

    Affiliation: Department of Bacteriology, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom

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  • Ken C. Smith,

    Affiliation: Department of Pathology and Infectious Diseases, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts, United Kingdom

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  • Jan-Ingmar Flock mail

    jan-ingmar.flock@ki.se

    Affiliation: Department of Microbiology, Tumor and Cellbiology, Karolinska Institutet, Stockholm, Sweden

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  • Published: September 18, 2009
  • DOI: 10.1371/journal.ppat.1000584

About the Authors

Bengt Guss, Lars Frykberg
Department of Microbiology, Swedish University of Agricultural Sciences, Uppsala, Sweden
Margareta Flock, Jan-Ingmar Flock
Department of Microbiology, Tumor and Cellbiology, Karolinska Institutet, Stockholm, Sweden
Andrew S. Waller, Carl Robinson
Department of Bacteriology, Animal Health Trust, Lanwades Park, Kentford, Newmarket, United Kingdom
Ken C. Smith
Department of Pathology and Infectious Diseases, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts, United Kingdom

Corresponding Author

Email: jan-ingmar.flock@ki.se

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BG MF LF ASW CR JIF. Performed the experiments: BG MF LF ASW CR KCS JIF. Analyzed the data: BG MF LF ASW CR KCS JIF. Contributed reagents/materials/analysis tools: KCS. Wrote the paper: JIF.