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Research Article

A Cyclic GMP Signalling Module That Regulates Gliding Motility in a Malaria Parasite

  • Robert W. Moon,

    Affiliations: Wellcome Trust Sanger Institute, Cambridge Hinxton, United Kingdom, Imperial College London, Department of Cell and Molecular Biology, London, United Kingdom

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  • Cathy J. Taylor,

    Affiliation: Department of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom

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  • Claudia Bex,

    Affiliation: Wellcome Trust Sanger Institute, Cambridge Hinxton, United Kingdom

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  • Rebecca Schepers,

    Affiliation: Imperial College London, Department of Cell and Molecular Biology, London, United Kingdom

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  • David Goulding,

    Affiliation: Wellcome Trust Sanger Institute, Cambridge Hinxton, United Kingdom

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  • Chris J. Janse,

    Affiliation: Department of Parasitology, Centre of Infectious Diseases, Leiden University Medical Centre, Leiden, The Netherlands

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  • Andrew P. Waters,

    Affiliation: Wellcome Trust Centre of Molecular Parasitology and Division of Infection and Immunity, University of Glasgow, Glasgow, United Kingdom

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  • David A. Baker,

    Affiliation: Department of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom

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  • Oliver Billker mail

    ob4@sanger.ac.uk

    Affiliations: Wellcome Trust Sanger Institute, Cambridge Hinxton, United Kingdom, Imperial College London, Department of Cell and Molecular Biology, London, United Kingdom

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  • Published: September 25, 2009
  • DOI: 10.1371/journal.ppat.1000599

About the Authors

Robert W. Moon, Claudia Bex, David Goulding, Oliver Billker
Wellcome Trust Sanger Institute, Cambridge Hinxton, United Kingdom
Robert W. Moon, Rebecca Schepers, Oliver Billker
Imperial College London, Department of Cell and Molecular Biology, London, United Kingdom
Cathy J. Taylor, David A. Baker
Department of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom
Chris J. Janse
Department of Parasitology, Centre of Infectious Diseases, Leiden University Medical Centre, Leiden, The Netherlands
Andrew P. Waters
Wellcome Trust Centre of Molecular Parasitology and Division of Infection and Immunity, University of Glasgow, Glasgow, United Kingdom

Corresponding Author

Email: ob4@sanger.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RWM CJT CB RS DG CJJ APW DAB OB. Performed the experiments: RWM CJT CB RS DG CJJ. Analyzed the data: RWM CJT CB RS DG CJJ APW DAB OB. Contributed reagents/materials/analysis tools: RWM CJT CB DG CJJ APW DAB OB. Wrote the paper: RWM OB.