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Research Article

RNase L Mediated Protection from Virus Induced Demyelination

  • Derek D. C. Ireland,

    Affiliation: Department of Neuroscience, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio, United States of America

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  • Stephen A. Stohlman,

    Affiliation: Department of Neuroscience, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio, United States of America

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  • David R. Hinton,

    Affiliation: Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, California, United States of America

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  • Parul Kapil,

    Affiliations: Department of Neuroscience, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio, United States of America, Department of Biological, Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio, United States of America

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  • Robert H. Silverman,

    Affiliation: Department of Cancer Biology, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio, United States of America

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  • Roscoe A. Atkinson,

    Affiliation: Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, California, United States of America

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  • Cornelia C. Bergmann mail

    bergmac@ccf.org

    Affiliation: Department of Neuroscience, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio, United States of America

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  • Published: October 02, 2009
  • DOI: 10.1371/journal.ppat.1000602

About the Authors

Derek D. C. Ireland, Stephen A. Stohlman, Parul Kapil, Cornelia C. Bergmann
Department of Neuroscience, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio, United States of America
David R. Hinton, Roscoe A. Atkinson
Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, California, United States of America
Parul Kapil
Department of Biological, Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio, United States of America
Robert H. Silverman
Department of Cancer Biology, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio, United States of America

Corresponding Author

Email: bergmac@ccf.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DDCI SAS CCB. Performed the experiments: DDCI PK. Analyzed the data: DDCI SAS DRH PK RHS RAA CCB. Contributed reagents/materials/analysis tools: CCB. Wrote the paper: DDCI SAS DRH RHS CCB.