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Research Article

The Leishmania donovani Lipophosphoglycan Excludes the Vesicular Proton-ATPase from Phagosomes by Impairing the Recruitment of Synaptotagmin V

  • Adrien F. Vinet,

    Affiliation: INRS-Institut Armand-Frappier and Centre for Host-Parasite Interactions, Laval, Québec, Canada

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  • Mitsunori Fukuda,

    Affiliation: Department of Developmental Biology and Neurosciences, Tohoku University, Sendai, Miyagi, Japan

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  • Salvatore J. Turco,

    Affiliation: Department of Biochemistry, University of Kentucky, Lexington, Kentucky, United States of America

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  • Albert Descoteaux mail

    albert.descoteaux@iaf.inrs.ca

    Affiliation: INRS-Institut Armand-Frappier and Centre for Host-Parasite Interactions, Laval, Québec, Canada

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  • Published: October 16, 2009
  • DOI: 10.1371/journal.ppat.1000628

About the Authors

Adrien F. Vinet, Albert Descoteaux
INRS-Institut Armand-Frappier and Centre for Host-Parasite Interactions, Laval, Québec, Canada
Mitsunori Fukuda
Department of Developmental Biology and Neurosciences, Tohoku University, Sendai, Miyagi, Japan
Salvatore J. Turco
Department of Biochemistry, University of Kentucky, Lexington, Kentucky, United States of America

Corresponding Author

Email: albert.descoteaux@iaf.inrs.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AFV AD. Performed the experiments: AFV. Analyzed the data: AFV AD. Contributed reagents/materials/analysis tools: MF SJT. Wrote the paper: AFV AD.