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Research Article

Dengue Virus Capsid Protein Usurps Lipid Droplets for Viral Particle Formation

  • Marcelo M. Samsa,

    Affiliation: Fundación Instituto Leloir-CONICET, Buenos Aires, Argentina

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  • Juan A. Mondotte,

    Affiliation: Fundación Instituto Leloir-CONICET, Buenos Aires, Argentina

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  • Nestor G. Iglesias,

    Affiliation: Fundación Instituto Leloir-CONICET, Buenos Aires, Argentina

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  • Iranaia Assunção-Miranda,

    Affiliation: Instituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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  • Giselle Barbosa-Lima,

    Affiliation: Laboratório de Imunofarmacologia, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil

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  • Andrea T. Da Poian,

    Affiliation: Instituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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  • Patricia T. Bozza,

    Affiliation: Laboratório de Imunofarmacologia, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil

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  • Andrea V. Gamarnik mail

    agamarnik@leloir.org.ar

    Affiliation: Fundación Instituto Leloir-CONICET, Buenos Aires, Argentina

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  • Published: October 23, 2009
  • DOI: 10.1371/journal.ppat.1000632

About the Authors

Marcelo M. Samsa, Juan A. Mondotte, Nestor G. Iglesias, Andrea V. Gamarnik
Fundación Instituto Leloir-CONICET, Buenos Aires, Argentina
Iranaia Assunção-Miranda, Andrea T. Da Poian
Instituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
Giselle Barbosa-Lima, Patricia T. Bozza
Laboratório de Imunofarmacologia, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil

Corresponding Author

Email: agamarnik@leloir.org.ar

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MMS JAM NGI IAM GBL ATDP PTB AVG. Performed the experiments: MMS JAM NGI IAM GBL. Analyzed the data: MMS JAM NGI ATDP PTB AVG. Contributed reagents/materials/analysis tools: PTB. Wrote the paper: MMS JAM NGI AVG.