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Research Article

Targeting the Replication Initiator of the Second Vibrio Chromosome: Towards Generation of Vibrionaceae-Specific Antimicrobial Agents

  • Yoshiharu Yamaichi,

    Affiliation: Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School and Howard Hughes Medical Institute, Boston, Massachusetts, United States of America

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  • Stéphane Duigou,

    Affiliation: Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School and Howard Hughes Medical Institute, Boston, Massachusetts, United States of America

    Current address: CNRS, Centre de Génétique Moléculaire, UPR 2167, Gif-sur-Yvette, France

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  • Elizabeth A. Shakhnovich,

    Affiliation: Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School and Howard Hughes Medical Institute, Boston, Massachusetts, United States of America

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  • Matthew K. Waldor mail

    mwaldor@rics.bwh.harvard.edu

    Affiliation: Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School and Howard Hughes Medical Institute, Boston, Massachusetts, United States of America

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  • Published: November 20, 2009
  • DOI: 10.1371/journal.ppat.1000663

About the Authors

Yoshiharu Yamaichi, Stéphane Duigou, Elizabeth A. Shakhnovich, Matthew K. Waldor
Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School and Howard Hughes Medical Institute, Boston, Massachusetts, United States of America

Corresponding Author

Email: mwaldor@rics.bwh.harvard.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YY SD EAS MKW. Performed the experiments: YY SD EAS. Analyzed the data: YY SD EAS MKW. Contributed reagents/materials/analysis tools: YY SD. Wrote the paper: YY SD MKW.