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Research Article

IlsA, A Unique Surface Protein of Bacillus cereus Required for Iron Acquisition from Heme, Hemoglobin and Ferritin

  • Nadine Daou,

    Affiliations: INRA-UR1249 Génétique Microbienne et Environnement, La Minière, Guyancourt, France, Laboratoire de Biotechnologie, Université Saint-Joseph, Beyrouth, Lebanon

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  • Christophe Buisson,

    Affiliation: INRA-UR1249 Génétique Microbienne et Environnement, La Minière, Guyancourt, France

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  • Michel Gohar,

    Affiliation: INRA-UR1249 Génétique Microbienne et Environnement, La Minière, Guyancourt, France

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  • Jasmina Vidic,

    Affiliation: INRA-UR892 Unité de Biologie Physico-Chimique des Prions, Virologie et Immunologie Moléculaires, Jouy en Josas, France

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  • Hélène Bierne,

    Affiliation: Unité Interaction Bactéries Cellules, Institut Pasteur, INSERM U604 – INRA USC2020, Paris, France

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  • Mireille Kallassy,

    Affiliation: Laboratoire de Biotechnologie, Université Saint-Joseph, Beyrouth, Lebanon

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  • Didier Lereclus,

    Affiliation: INRA-UR1249 Génétique Microbienne et Environnement, La Minière, Guyancourt, France

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  • Christina Nielsen-LeRoux mail

    christina.nielsen@jouy.inra.fr

    Affiliation: INRA-UR1249 Génétique Microbienne et Environnement, La Minière, Guyancourt, France

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  • Published: November 26, 2009
  • DOI: 10.1371/journal.ppat.1000675

About the Authors

Nadine Daou, Christophe Buisson, Michel Gohar, Didier Lereclus, Christina Nielsen-LeRoux
INRA-UR1249 Génétique Microbienne et Environnement, La Minière, Guyancourt, France
Nadine Daou, Mireille Kallassy
Laboratoire de Biotechnologie, Université Saint-Joseph, Beyrouth, Lebanon
Jasmina Vidic
INRA-UR892 Unité de Biologie Physico-Chimique des Prions, Virologie et Immunologie Moléculaires, Jouy en Josas, France
Hélène Bierne
Unité Interaction Bactéries Cellules, Institut Pasteur, INSERM U604 – INRA USC2020, Paris, France

Corresponding Author

Email: christina.nielsen@jouy.inra.fr

Competing Interests

The authors are in the process of patenting IlsA, which may benefit from publication of this manuscript.

Author Contributions

Conceived and designed the experiments: ND MG MK CNL. Performed the experiments: ND CB JV HB. Analyzed the data: ND DL CNL. Contributed reagents/materials/analysis tools: MG JV HB MK. Wrote the paper: ND CNL. Helpful discussions: MG. Co-directeur of PhD thesis for N. Daou: MK. Participated in discussion and writing, head of lab where experiments were performed: DL.