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Research Article

Central Role of the Holliday Junction Helicase RuvAB in vlsE Recombination and Infectivity of Borrelia burgdorferi

  • Tao Lin equal contributor,

    equal contributor Contributed equally to this work with: Tao Lin, Lihui Gao

    Affiliation: Department of Pathology and Laboratory Medicine, Medical School, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

    X
  • Lihui Gao equal contributor,

    equal contributor Contributed equally to this work with: Tao Lin, Lihui Gao

    Affiliation: Department of Pathology and Laboratory Medicine, Medical School, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

    X
  • Diane G. Edmondson,

    Affiliation: Department of Pathology and Laboratory Medicine, Medical School, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

    X
  • Mary B. Jacobs,

    Affiliation: Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Tulane University Health Sciences Center, Covington, Louisiana, United States of America

    X
  • Mario T. Philipp,

    Affiliation: Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Tulane University Health Sciences Center, Covington, Louisiana, United States of America

    X
  • Steven J. Norris mail

    Steven.J.Norris@uth.tmc.edu

    Affiliations: Department of Pathology and Laboratory Medicine, Medical School, University of Texas Health Science Center at Houston, Houston, Texas, United States of America, Department of Microbiology and Molecular Genetics, Medical School, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

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  • Published: December 04, 2009
  • DOI: 10.1371/journal.ppat.1000679

About the Authors

Tao Lin, Lihui Gao, Diane G. Edmondson, Steven J. Norris
Department of Pathology and Laboratory Medicine, Medical School, University of Texas Health Science Center at Houston, Houston, Texas, United States of America
Mary B. Jacobs, Mario T. Philipp
Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Tulane University Health Sciences Center, Covington, Louisiana, United States of America
Steven J. Norris
Department of Microbiology and Molecular Genetics, Medical School, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Corresponding Author

Email: Steven.J.Norris@uth.tmc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TL LG DGE MTP SJN. Performed the experiments: TL LG DGE MBJ. Analyzed the data: TL LG DGE MBJ MTP SJN. Contributed reagents/materials/analysis tools: TL LG SJN. Wrote the paper: TL DGE MTP SJN.