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Research Article

BCA2/Rabring7 Promotes Tetherin-Dependent HIV-1 Restriction

  • Kei Miyakawa,

    Affiliations: AIDS Research Center, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan, Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan

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  • Akihide Ryo mail,

    aryo@nih.go.jp (AR); nyama@nih.go.jp (NY)

    Affiliation: AIDS Research Center, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan

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  • Tsutomu Murakami,

    Affiliation: AIDS Research Center, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan

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  • Kenji Ohba,

    Affiliation: AIDS Research Center, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan

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  • Shoji Yamaoka,

    Affiliation: Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan

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  • Mitsunori Fukuda,

    Affiliation: Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi, Japan

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  • John Guatelli,

    Affiliation: Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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  • Naoki Yamamoto mail

    aryo@nih.go.jp (AR); nyama@nih.go.jp (NY)

    Affiliation: AIDS Research Center, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan

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  • Published: December 18, 2009
  • DOI: 10.1371/journal.ppat.1000700

About the Authors

Kei Miyakawa, Akihide Ryo, Tsutomu Murakami, Kenji Ohba, Naoki Yamamoto
AIDS Research Center, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo, Japan
Kei Miyakawa, Shoji Yamaoka
Department of Molecular Virology, Graduate School of Medicine, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan
Mitsunori Fukuda
Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi, Japan
John Guatelli
Department of Medicine, University of California San Diego, La Jolla, California, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Analyzed the data: TM KO JG. Contributed reagents/materials/analysis tools: TM SY MF. Performed the research, collected and analyzed the data, and wrote the manuscript: KM. Designed and supervised research, collected and analyzed the data: AR. Designed the research, supervised, and commented on the manuscript: NY.