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Research Article

Bacterial Effector Binding to Ribosomal Protein S3 Subverts NF-κB Function

  • Xiaofei Gao,

    Affiliation: Department of Microbiology, Molecular Genetics, and Immunology, University of Kansas Medical Center, Kansas City, Kansas, United States of America

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  • Fengyi Wan,

    Affiliation: Laboratory of Immunology, National Institutes of Allergy and Infectious Diseases, Bethesda, Maryland, United States of America

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  • Kristina Mateo,

    Affiliation: Department of Veterinary Science, South Dakota State University, Brookings, South Dakota, United States of America

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  • Eduardo Callegari,

    Affiliation: Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, South Dakota, United States of America

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  • Dan Wang,

    Affiliation: Department of Veterinary Science, South Dakota State University, Brookings, South Dakota, United States of America

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  • Wanyin Deng,

    Affiliation: Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

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  • Jose Puente,

    Affiliation: Departamento de Microbiología Molecular, Universidad Nacional Autónoma de México, Cuernavaca, Mexico

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  • Feng Li,

    Affiliation: Department of Veterinary Science, South Dakota State University, Brookings, South Dakota, United States of America

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  • Michael S. Chaussee,

    Affiliation: Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, South Dakota, United States of America

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  • B. Brett Finlay,

    Affiliation: Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

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  • Michael J. Lenardo,

    Affiliation: Laboratory of Immunology, National Institutes of Allergy and Infectious Diseases, Bethesda, Maryland, United States of America

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  • Philip R. Hardwidge mail

    phardwidge@kumc.edu

    Affiliation: Department of Microbiology, Molecular Genetics, and Immunology, University of Kansas Medical Center, Kansas City, Kansas, United States of America

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  • Published: December 24, 2009
  • DOI: 10.1371/journal.ppat.1000708

About the Authors

Xiaofei Gao, Philip R. Hardwidge
Department of Microbiology, Molecular Genetics, and Immunology, University of Kansas Medical Center, Kansas City, Kansas, United States of America
Fengyi Wan, Michael J. Lenardo
Laboratory of Immunology, National Institutes of Allergy and Infectious Diseases, Bethesda, Maryland, United States of America
Kristina Mateo, Dan Wang, Feng Li
Department of Veterinary Science, South Dakota State University, Brookings, South Dakota, United States of America
Eduardo Callegari, Michael S. Chaussee
Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, South Dakota, United States of America
Wanyin Deng, B. Brett Finlay
Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada
Jose Puente
Departamento de Microbiología Molecular, Universidad Nacional Autónoma de México, Cuernavaca, Mexico

Corresponding Author

Email: phardwidge@kumc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XG PRH. Performed the experiments: XG FW KM EC PRH. Analyzed the data: XG FW FL MJL PRH. Contributed reagents/materials/analysis tools: FW KM EC DW WD JP FL MSC BBF MJL. Wrote the paper: XG PRH.