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Research Article

The Type III Secretion Effector NleE Inhibits NF-κB Activation

  • Chen Nadler,

    Affiliation: Department of Microbiology and Molecular Genetics, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel

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  • Kobi Baruch,

    Affiliation: Department of Microbiology and Molecular Genetics, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel

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  • Simi Kobi,

    Affiliation: Department of Microbiology and Molecular Genetics, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel

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  • Erez Mills,

    Affiliation: Department of Microbiology and Molecular Genetics, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel

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  • Gili Haviv,

    Affiliation: Department of Microbiology and Molecular Genetics, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel

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  • Marganit Farago,

    Affiliation: Department of Immunology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel

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  • Irit Alkalay,

    Affiliation: Department of Immunology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel

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  • Sina Bartfeld,

    Affiliation: Department Molecular Biology, MPI for Infection Biology, Berlin, Germany

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  • Thomas F. Meyer,

    Affiliation: Department Molecular Biology, MPI for Infection Biology, Berlin, Germany

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  • Yinon Ben-Neriah,

    Affiliation: Department of Immunology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel

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  • Ilan Rosenshine mail

    ilanr@ekmd.huji.ac.il

    Affiliation: Department of Microbiology and Molecular Genetics, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel

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  • Published: January 29, 2010
  • DOI: 10.1371/journal.ppat.1000743

About the Authors

Chen Nadler, Kobi Baruch, Simi Kobi, Erez Mills, Gili Haviv, Ilan Rosenshine
Department of Microbiology and Molecular Genetics, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel
Marganit Farago, Irit Alkalay, Yinon Ben-Neriah
Department of Immunology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel
Sina Bartfeld, Thomas F. Meyer
Department Molecular Biology, MPI for Infection Biology, Berlin, Germany

Corresponding Author

Email: ilanr@ekmd.huji.ac.il

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CN KB SB IR. Performed the experiments: CN KB SK EM GH MF IA SB. Analyzed the data: CN KB SK SB TFM YBN IR. Wrote the paper: CN KB SB IR.