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Research Article

Neutrophil-Derived CCL3 Is Essential for the Rapid Recruitment of Dendritic Cells to the Site of Leishmania major Inoculation in Resistant Mice

  • Mélanie Charmoy,

    Affiliation: Department of Biochemistry, WHO Immunology Research and Training Center, University of Lausannne, Epalinges, Switzerland

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  • Saskia Brunner-Agten,

    Affiliation: Department of Biochemistry, WHO Immunology Research and Training Center, University of Lausannne, Epalinges, Switzerland

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  • David Aebischer,

    Affiliation: Department of Biochemistry, WHO Immunology Research and Training Center, University of Lausannne, Epalinges, Switzerland

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  • Floriane Auderset,

    Affiliation: Department of Biochemistry, WHO Immunology Research and Training Center, University of Lausannne, Epalinges, Switzerland

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  • Pascal Launois,

    Affiliation: Department of Biochemistry, WHO Immunology Research and Training Center, University of Lausannne, Epalinges, Switzerland

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  • Geneviève Milon,

    Affiliation: Institut Pasteur, Département de Parasitologie et Mycologie, Unité d'Immunophysiologie et Parasitisme Intracellulaire, Paris, France

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  • Amanda E. I. Proudfoot,

    Affiliation: Merck-Serono Geneva Research Center, Geneva, Switzerland

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  • Fabienne Tacchini-Cottier mail

    Fabienne.Tacchini-Cottier@unil.ch

    Affiliation: Department of Biochemistry, WHO Immunology Research and Training Center, University of Lausannne, Epalinges, Switzerland

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  • Published: February 05, 2010
  • DOI: 10.1371/journal.ppat.1000755

About the Authors

Mélanie Charmoy, Saskia Brunner-Agten, David Aebischer, Floriane Auderset, Pascal Launois, Fabienne Tacchini-Cottier
Department of Biochemistry, WHO Immunology Research and Training Center, University of Lausannne, Epalinges, Switzerland
Geneviève Milon
Institut Pasteur, Département de Parasitologie et Mycologie, Unité d'Immunophysiologie et Parasitisme Intracellulaire, Paris, France
Amanda E. I. Proudfoot
Merck-Serono Geneva Research Center, Geneva, Switzerland

Corresponding Author

Email: Fabienne.Tacchini-Cottier@unil.ch

Competing Interests

AEIP is an employee of Merck-Serono Research center in Geneva. All of the other authors declare no conflict of interest.

Author Contributions

Conceived and designed the experiments: AEIP FTC. Performed the experiments: MC SBA DA FA. Analyzed the data: MC FTC. Contributed reagents/materials/analysis tools: GM AEIP. Wrote the paper: FTC. Contributed to the design of the experiments: MC. Contributed to the writing of the manuscript: MC GM. Input in the design and analysis of data: PL.